Antibody
- +1 609-736-0910
- [email protected]
- 90 State Street, STE 700 Office 40, Albany, NY 12207 United States
Product Background
Catalog Number |
ADT1005 |
Product Name |
High-Quality Abciximab Biosimilar: (ITGA2B/ITGB3)- Research Grade |
Chemical Formula |
C6462H9964N1690O2049S48 |
Tags |
biosimilar antibodies, biosimilar monoclonal antibodies, Abciximab Biosimilar, Abciximab, ITGA2B, ITGB3,143653-53-6 |
Clonity |
Monoclonal |
Host |
CHO Cells |
Target |
ITGA2B_ITGB3[Homo sapiens] |
CAS Number |
143653-53-6 |
Molecular Weigh |
145.65 KDa |
Alias |
c7E3 |
Isotype |
Fab-G1 Kappa |
Research area |
Cardiovascular |
Application |
ELISA, IHC, IF, IP, Flow Cyt, FuncS |
Size |
1mg, 5mg |
Concentration |
batch dependent |
Buffer |
Supplied in PBS, PH7.5 |
Purity |
>95% as determined by SDS-PAGE |
Storage |
Store at -20 °C for 12 months. Store at -80 °C for long term storage. Avoid repeated freezing and thawing. |
Metabolism |
Most likely removed by opsonization via the reticuloendothelial system when bound to platelets, or by human antimurine antibody production. Excreted renally. |
Shipping Condition |
Shipped on ice packs. |
Note |
This product is for research use only. |
FAQ
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Does this Biosimilar antibody have the same sequence as its corresponding therapeutic antibody?
Biosimilar antibodies are highly similar to their reference products but may have slight differences due to the inherent variability of biological systems. While the amino acid sequences of biosimilar antibodies are designed to closely match those of the reference antibodies, minor differences in glycosylation patterns or post-translational modifications may exist. However, these differences are not expected to affect the overall safety or efficacy of the biosimilar.
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What is a direct ELISA?
A direct enzyme-linked immunosorbent assay (ELISA) is a type of immunoassay used to detect the presence of a specific antigen in a sample. In a direct ELISA, the antigen is immobilized or coated onto the surface of a microtiter plate well. Direct ELISA is a simple and straightforward method for the detection and quantification of specific antigens in a sample. It is commonly used in research laboratories, clinical diagnostics, and biotechnology applications.
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At what concentration/dilution should I use my antibody in a particular method?
For western blotting and ELISA, antibody concentrations are typically in the range of 0.1-10 μg/mL.
For immunohistochemistry and immunofluorescence, antibody dilutions are often optimized empirically and may range from 1:50 to 1:500 or higher.
For flow cytometry, antibody concentrations may vary depending on the specific fluorophores used and the cell type being analyzed.
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What expression system are your antibodies manufactured in?
Antibodies can be produced in mammalian cell lines such as Chinese hamster ovary (CHO) cells, NS0 cells, or human embryonic kidney (HEK) cells. Antibodies can also be expressed in bacterial hosts such as Escherichia coli (E. coli).Yeast expression systems, such as Saccharomyces cerevisiae or Pichia pastoris, are used for the production of antibodies that require eukaryotic expression but do not require complex post-translational modifications. Antibodies can also be expressed in insect cell lines such as Spodoptera frugiperda (Sf9) cells using the baculovirus expression system. Alpha Lifetech has multiple antibody expression systems for customers to choose the appropriate one.