ADT1017-Afelimomab Biosimilar-Anti-TNFSF2/TNF-alpha/TNFA mAb-Research Grade

Catalog Number

ADT1017

Product Name

ADT1017-Afelimomab Biosimilar-Anti-TNFSF2/TNF-alpha/TNFA mAb-Research Grade

Clonity

Monoclonal

Alternate Names

mouse tnf alpha,  anti tnf alpha,  tnf alpha monoclonal antibody,  human tnf alpha,  anti-tnfa antibody,  anti-tnfa antibody,  anti tnfa antibody,  recombinant tnfa,  tnfa antibody,  anti-tnfa monoclonal antibody,  tnfa antibodies,  tnfa recombinant antibody,  tnfa blocking antibody,  TNFSF2 recombinant antibody,  TNFSF2 blocking antibody

Alias

Host

CHO Cells

Species

Mouse

Target

TNF alpha/TNFA/TNFSF2

Gene ID

21926

Isotype

F(ab')2-G3 Kappa

Size

1mg, 5mg

Research Area

Immunology

CAS Number

156227-98-4

Product Description

Afelimomab (also known as Fab 2 or MAK 195F) is an anti-TNF-α monoclonal antibody. Administration of 195F reduces the concentration of interleukin-6 in patients with sepsis.

Mechanism of Action

Afelimomab is a monoclonal antibody that targets specific antigens associated with disease states,  often cancer or inflammatory conditions.

Metabolism

As a full-length monoclonal antibody,  Afelimomab typically has a long half-life,  allowing for sustained therapeutic effects. Its distribution and clearance are influenced by factors like molecular size and glycosylation.

Application

Neut,  ELISA,  IF,  IP,  Functional assay,  FC,  ICC

Purity

>95% as determined by SDS-PAGE

Concentration

batch dependent

Buffer

Supplied in PBS,  PH7.5

Storage

Store at -20 °C for 12 months. Store at -80 °C for long term storage.

Shipping Condition

Shipped on ice packs.

Note

This product is for research use only.

Reactivity

Mouse

Reference