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ADT1031-Anatumomab Mafenatox Biosimilar-Anti-TAG-72 mAb-Research Grade
Antibody

ADT1031-Anatumomab Mafenatox Biosimilar-Anti-TAG-72 mAb-Research Grade

  • Catalog Number ADT1031
  • Host CHO Cells
  • Species Human
  • Target TAG-72
  • Application ELISA, WB

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Product Background

TAG-72 is a high-molecular-weight mucin-like glycoprotein characterized by heavy glycosylation, with carbohydrate chains comprising up to 50% of its mass. It forms a complex antigenic structure on the cell surface, though its precise genetic origin remains less defined compared to other mucins (e.g., MUC1).

Product Specification

Catalog Number

ADT1031

Product Name

ADT1031-Anatumomab Mafenatox Biosimilar-Anti-TAG-72 mAb-Research Grade

Clonity

Monoclonal

Alternate Names

recombinant TAG-72 antibody,  Anti TAG-72 antibody,  tumor associated glycoprotein 72 antibody,  anti-mouse TAG-72 antibody,  anti-TAG-72 antibody,  anti TAG-72 antibody,  recombinant TAG-72,  TAG-72 antibody,  anti-TAG-72 monoclonal antibody,  TAG-72 antibodies,  TAG-72 recombinant antibody,  TAG-72 blocking antibody

Alias

ABR-214936,  pMB125

Host

CHO Cells

Species

Human

Target

TAG-72

Gene ID

182875

Isotype

Fab-G1 Kappa

Size

1mg, 5mg

Research Area

Immunology

Product Description

Anatumomab mafenatox is a mouse monoclonal antibody,  which acts as a tumor-targeted superantigen.

Application

ELISA, WB

Purity

>95% as determined by SDS-PAGE

Concentration

batch dependent

Buffer

Supplied in PBS,  PH7.5

Storage

Store at -20 °C for 12 months. Store at -80 °C for long term storage.

Shipping Condition

Shipped on ice packs.

Note

This product is for research use only.

Reference

1. Jansen L,  et al. TAG-72: A comprehensive review of its role as a cancer biomarker and therapeutic target. Cancer Immunology,  Immunotherapy. 2020 Oct;69(10):2019-2034. PMID 32633675
2. Carpentier S,  et al. The use of TAG-72 as a target for antibody-based therapies in gastrointestinal cancers. Journal of Clinical Oncology. 2019 Sep 20;37(27):2461-2470. PMID 31249773
3. Kumar V,  et al. Characterization and therapeutic potential of TAG-72 in cancer treatment. OncoTargets and Therapy. 2019 Aug;12:4567-4582. PMID 31343672