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Product Background
Catalog Number |
ADT1043 |
Product Name |
ADT1043-Anti-CD28 Biosimilar Antibody– Anti-CD28(Tp44) mAb – Research Grade |
Isotype |
man IgG4 |
Clonity |
Monoclonal |
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Alternate Names anti cd28, anti cd28 antibody, cd28 antibody, human cd28, recombinant cd28, anti human cd28, monoclonal cd28 antibody, antibody cd28
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Official Symbol |
CD28 |
Species |
Human |
Expression Host |
CHO Cells |
Reactivity |
Human |
Gene ID |
940 |
Molecular Weight |
150.00 KDa |
Mechanism of Action |
Anti-CD28 is designed to bind to the CD28 receptor on T cells, which plays a crucial role in T cell activation and proliferation. |
Metabolism |
Anti-CD28 has a long half-life typical of monoclonal antibodies. It is distributed into the bloodstream and tissues. |
Size |
1mg,5mg |
Research Area |
Immunology |
Application |
Elisa, WB |
Purity |
>95% as determined by SDS-PAGE |
Concentration |
Batch dependent |
Buffer |
Supplied in PBS, PH7.5 |
Storage |
Store at -20 °C for 12 months. Store at -80 °C for long term storage. |
Shipping Condition |
Shipped on ice packs. |
Note |
This product is for research use only. |
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Reference 1.Pulanco MC, et al. Cell Mol Immunol, 2023 Jul. PMID 37069229
2.Liu TH, et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2022 Dec. PMID 36476893
3.Hodge G, et al. Clin Exp Immunol, 2022 May 12. PMID 35553638
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FAQ
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What is a biosimilar?
A biosimilar is a biological product that is highly similar to an existing approved reference biological product (also known as the originator or reference product), with no clinically meaningful differences in terms of safety, purity, and potency. Biosimilars are developed to be highly similar to the reference product in terms of structure, function, pharmacokinetics, and clinical efficacy. Alpha Lifetech can provide biosimilar antibody products.
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How can I obtain COA of the reagent that I received?
Please contact us via email info@alphalifetech.com for detailed information about the product.
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Why choose Alpha Lifetech’s product?
Alpha Lifetech's products are chosen for their quality, reliability, and competitive pricing. Our biosimilar antibodies undergo thorough development and testing processes to ensure they meet regulatory requirements and deliver comparable performance to reference products. We prioritize customer satisfaction and strive to provide cost-effective solutions without compromising on quality. -
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How to purify your antibodies?
Protein A/G Chromatography: Protein A and Protein G are affinity chromatography matrices that specifically bind to the Fc region of antibodies, allowing for their purification from complex mixtures.
Ion Exchange Chromatography: Ion exchange chromatography separates proteins based on their net charge at a specific pH.
Size Exclusion Chromatography: Size exclusion chromatography (SEC), also known as gel filtration chromatography, separates proteins based on their size and shape.
Affinity Tag Purification: Some recombinant antibodies are engineered with affinity tags (e.g., His-tag, FLAG-tag) that facilitate purification. Affinity tag purification involves using specific affinity resins or columns that bind to the tag, allowing for purification of the tagged antibodies. Alpha Lifetech has multiple antibody purification strategies. Please contact us via email info@alphalifetech.com for more detailed information.