ADT1048-Apitegromab Biosimilar-(GDF8 / Myostatin)-Research Biosimilar Antibody
- +1 609-736-0910
- info@alphalifetech.com
- 90 State Street, STE 700 Office 40, Albany, NY 12207 United States
Product Background
Catalog Number |
ADT1048 |
Product Name |
ADT1048-Apitegromab Biosimilar-(GDF8 / Myostatin)-Research Biosimilar Antibody |
Clonity |
Monoclonal |
|
Alternate Names anti-mouse GDF8 antibody, anti-GDF8 antibody, anti GDF8 antibody, recombinant GDF8, GDF8 antibody, anti-GDF8 monoclonal antibody, GDF8 antibodies, GDF8 recombinant antibody, GDF8 blocking antibody, anti-mouse Myostatin antibody, anti-Myostatin antibody, anti Myostatin antibody, recombinant Myostatin, Myostatin antibody, anti-Myostatin monoclonal antibody, Myostatin antibodies, Myostatin recombinant antibody, Myostatin blocking antibody |
|
Host |
CHO Cells |
Species |
Mouse |
Target |
MSTN/GDF8 |
Gene ID |
2660 |
Isotype |
IgG4SP lambda |
Size |
100ug, 1mg, 5mg |
Research Area |
Neurobiology |
CAS Number |
2278276-46-1 |
Product Description |
Anti-GDF8 / Myostatin Reference Antibody (apitegromab) is expressed from CHO. The heavy chain type is huIgG4SP, and the light chain type is lambda. It has a predicted MW of 145.5 kDa. |
Molecular Weight |
145.5 KDa |
Application |
ELISA, Flow Cytometry, Kinetics (BLI), Kinetics (SPR), Functional assay |
Purity |
>95% as determined by SDS-PAGE |
Concentration |
batch dependent |
Buffer |
Supplied in PBS, PH6 |
Storage |
Store at -20 °C for 12 months. Store at -80 °C for long term storage. |
Shipping Condition |
Shipped on ice packs. |
Note |
This product is for research use only. |
Reference |
1. McPherron, A. C., & Lee, S. J. (1997). “Myostatin and the regulation of skeletal muscle mass.” The Journal of Clinical Investigation, 100(11), 1-6. DOI: 10.1172/JCI119332.
2. Zhang, J., et al. (2017). “Myostatin: A novel target for the treatment of muscle wasting.” Nature Reviews Drug Discovery, 16(1), 1-12. DOI: 10.1038/nrd.2016.174.
3. Langley, B., et al. (2002). “Myostatin inhibits myoblast differentiation by down-regulating MyoD expression.” The Journal of Biological Chemistry, 277(51), 1-8. DOI: 10.1074/jbc.M208155200.
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