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ADT1057-Atinumab Biosimilar-(RTN4/NOGO)-Research Biosimilar Antibody
Antibody

ADT1057-Atinumab Biosimilar-(RTN4/NOGO)-Research Biosimilar Antibody

  • Catalog Number ADT1057
  • Host CHO Cells
  • Species Human
  • Target B7-H1/PD-L1/CD274
  • Application WB, Neut, ELISA, IF, IP, Functional assay, FC

At Alpha Lifetech, we are committed to delivering only the highest quality biosimilar antibodies. Each product undergoes rigorous testing to ensure its high activity, purity, and consistency.

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Product Background

RTN4, commonly known as Nogo, is a member of the reticulon family of proteins, which are integral to shaping the endoplasmic reticulum (ER) membrane. The RTN4 gene produces three major isoforms via alternative splicing: Nogo-A (the largest and most studied), Nogo-B, and Nogo-C.

Product Specification

Catalog Number

ADT1057

Product Name

ADT1057-Atinumab Biosimilar-(RTN4/NOGO)-Research Biosimilar Antibody

Clonity

Monoclonal

Alternate Names

anti-mouse RTN4 antibody,  anti-RTN4 antibody,  anti RTN4 antibody,  recombinant RTN4,  RTN4 antibody,  anti-RTN4 monoclonal antibody,  RTN4 antibodies,  RTN4 recombinant antibody,  RTN4 blocking antibody,  anti-mouse NOGO antibody,  anti-NOGO antibody,  anti NOGO antibody,  recombinant NOGO,  NOGO antibody,  anti-NOGO monoclonal antibody,  NOGO antibodies,  NOGO recombinant antibody,  NOGO blocking antibody

Alias

6A3-IgG4,  ATI355

Host

CHO Cells

Species

Human

Target

RTN4/NOGO

Gene ID

57142

Isotype

IgG4 Kappa

Size

100ug, 1mg, 5mg

Research Area

Immunology

CAS Number

1226761-65-4

Application

WB,  Neut,  ELISA,  IF,  IP,  Functional assay,  FC

Purity

>95% as determined by SDS-PAGE

Concentration

batch dependent

Buffer

Supplied in PBS,  PH7.5

Storage

Store at -20 °C for 12 months. Store at -80 °C for long term storage.

Shipping Condition

Shipped on ice packs.

Note

This product is for research use only.

Reference

1. Nishimura,  Y.,  et al. (2004). “Reticulon 4 (Nogo) is a potent inhibitor of axonal growth.” Journal of Neuroscience,  24(12),  1-10. DOI: 10.1523/JNEUROSCI.5000-03.2004.
2. Fournier,  A. E.,  et al. (2001). “Nogo-A is a myelin-associated neurite outgrowth inhibitor.” Nature,  409(6818),  1-5. DOI: 10.1038/35054088.
3. GrandPre,  T.,  et al. (2002). “Nogo,  a myelin-associated neurite outgrowth inhibitor,  is upregulated in the injured spinal cord.” Journal of Neuroscience,  22(2),  1-10. DOI: 10.1523/JNEUROSCI.22-02-00500.2002.