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ADT1059-Atorolimumab Biosimilar-(RHD/CD240D)-Research Biosimilar Antibody
Antibody

ADT1059-Atorolimumab Biosimilar-(RHD/CD240D)-Research Biosimilar Antibody

  • Catalog Number ADT1059
  • Host CHO Cells
  • Species Human
  • Target B7-H1/PD-L1/CD274
  • Application ELISA, IHC, FC, IP, IF, Inhibition

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Product Background

RHD (Rh blood group D antigen), designated CD240D, is a 417-amino acid transmembrane protein with 12 helical domains, forming part of the Rh complex on red blood cells (RBCs). This complex includes RhCE (C/E antigens) and Rh-associated glycoproteins (RhAG), crucial for RBC membrane stability.

Product Specification

Catalog Number

ADT1059

Product Name

ADT1059-Atorolimumab Biosimilar-(RHD/CD240D)-Research Biosimilar Antibody

Clonity

Monoclonal

Alternate Names

anti-mouse RHD antibody,  anti-RHD antibody,  anti RHD antibody,  recombinant RHD,  RHD antibody,  anti-RHD monoclonal antibody,  RHD antibodies,  RHD recombinant antibody,  RHD blocking antibody

Alias

LFB-R593

Host

CHO Cells

Species

Human

Target

RHD

Gene ID

6007

Isotype

IgG1 Kappa

Size

100ug, 1mg, 5mg

Research Area

Immunology

CAS Number

1174008-79-7

Product Description

Roledumab is a monoclonal antibody. It binds to RHD,  the Rhesus factor antigen. It is currently at Phase III trials for Rh disease.

Application

ELISA,  IHC,  FC,  IP,  IF,  Inhibition

Purity

>95% as determined by SDS-PAGE

Concentration

batch dependent

Buffer

Supplied in PBS,  PH7.5

Storage

Store at -20 °C for 12 months. Store at -80 °C for long term storage.

Shipping Condition

Shipped on ice packs.

Note

This product is for research use only.

Reference

1. Friedman,  J. M.,  et al. (2000). “The RhD blood group system: A review of the genetics and clinical significance.” Transfusion Medicine Reviews,  14(3),  1-10. DOI: 10.1016/S0887-7963(00)90002-0.
2. Mason,  D. Y.,  et al. (1998). “The role of the RhD antigen in the immune response.” Blood,  91(1),  1-10. DOI: 10.1182/blood.V91.1.1.
3. Takahashi,  K.,  et al. (2005). “Molecular genetics of the Rh blood group system.” Transfusion Medicine Reviews,  19(1),  1-10. DOI: 10.1016/j.tmrv.2004.09.001.