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Product Background
Catalog Number |
ADT1072 |
Product Name |
ADT1072-Batoclimab Biosimilar– Anti-FCGRT mAb – Research Grade |
Alias |
HL161 |
Isotype |
IgG1 Lambda |
Clonity |
Monoclonal |
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Alternate Names Batoclimab Biosimilar, FCGRT antibody, anti FCGRT antibody, FCGRT recombinant antibody, FCGRT blocking antibody |
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Official Symbol |
FCGRT |
Species |
Human |
Expression Host |
CHO Cells |
Reactivity |
Human |
Gene ID |
2217 |
CAS Number |
2187430-05-1 |
Product Description |
Batoclimab is under investigation in clinical trial NCT04428255 (A Clinical Study on the Efficacy and Safety of HBM9161 in Patients With ITP). |
Mechanism of Action |
Batoclimab is a monoclonal antibody that targets the neonatal Fc receptor (FcRn), which is involved in antibody recycling and regulation. |
Metabolism |
Batoclimab follows a typical monoclonal antibody pharmacokinetic profile with a long half-life. |
Size |
100ug,1mg,5mg |
Research Area |
Immunology |
Application |
Elisa, WB |
Purity |
>95% as determined by SDS-PAGE |
Concentration |
Batch dependent |
Buffer |
Supplied in PBS, PH7.5 |
Storage |
Store at -20 °C for 12 months. Store at -80 °C for long term storage. |
Shipping Condition |
Shipped on ice packs. |
Note |
This product is for research use only. |
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Reference 1.Pyzik M, et al. Nat Rev Immunol, 2023 Jul. PMID 36726033
2.Chen X, et al. mBio, 2022 Aug 30. PMID 35862785
3.Brinkhaus M, et al. Sci Rep, 2022 Jan 7. PMID 34996950
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FAQ
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What is a biosimilar?
A biosimilar is a biological product that is highly similar to an existing approved reference biological product (also known as the originator or reference product), with no clinically meaningful differences in terms of safety, purity, and potency. Biosimilars are developed to be highly similar to the reference product in terms of structure, function, pharmacokinetics, and clinical efficacy. Alpha Lifetech can provide biosimilar antibody products.
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How can I obtain COA of the reagent that I received?
Please contact us via email info@alphalifetech.com for detailed information about the product.
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Why choose Alpha Lifetech’s product?
Alpha Lifetech's products are chosen for their quality, reliability, and competitive pricing. Our biosimilar antibodies undergo thorough development and testing processes to ensure they meet regulatory requirements and deliver comparable performance to reference products. We prioritize customer satisfaction and strive to provide cost-effective solutions without compromising on quality. -
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How to purify your antibodies?
Protein A/G Chromatography: Protein A and Protein G are affinity chromatography matrices that specifically bind to the Fc region of antibodies, allowing for their purification from complex mixtures.
Ion Exchange Chromatography: Ion exchange chromatography separates proteins based on their net charge at a specific pH.
Size Exclusion Chromatography: Size exclusion chromatography (SEC), also known as gel filtration chromatography, separates proteins based on their size and shape.
Affinity Tag Purification: Some recombinant antibodies are engineered with affinity tags (e.g., His-tag, FLAG-tag) that facilitate purification. Affinity tag purification involves using specific affinity resins or columns that bind to the tag, allowing for purification of the tagged antibodies. Alpha Lifetech has multiple antibody purification strategies. Please contact us via email info@alphalifetech.com for more detailed information.