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ADT1139-Clivatuzumab Biosimilar-(MUC1/CD227)-Research Biosimilar Antibody
Antibody

ADT1139-Clivatuzumab Biosimilar-(MUC1/CD227)-Research Biosimilar Antibody

  • Catalog Number ADT1139
  • Host CHO Cells
  • Species Human
  • Target MUC1/CD227
  • Application Elisa, WB

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Product Background

MUC1 serves critical roles in lubrication, hydration, and pathogen defense by trapping microbes and particulates, while its cytoplasmic domain modulates cell adhesion and signaling pathways, including those involving ERK and NF-κB.

Product Specification

Catalog Number

ADT1139

Product Name

ADT1139-Clivatuzumab Biosimilar-(MUC1/CD227)-Research Biosimilar Antibody

Clonity

Monoclonal

Alternate Names

anti-mouse cd227 antibody,  anti-cd227 antibody,  anti cd227 antibody,  recombinant cd227,  muc1 antibody,  anti-cd227 monoclonal antibody,  cd227 antibodies,  cd227 recombinant antibody,  cd227 blocking antibody

Alias

CMB-401,  hCTMO1-calicheamicin,  CDP 671

Host

CHO Cells

Species

Human

Target

MUC1/CD227

Gene ID

4582

Isotype

IgG1-nd

Size

1mg, 5mg

Research Area

Immunology

Mechanism of Action

CMB-401 is a monoclonal antibody targeting specific antigens on cancer cells or immune cells.

Metabolism

CMB-401 follows the pharmacokinetic profile of monoclonal antibodies with a long half-life.

Application

Elisa,  WB

Purity

>95% as determined by SDS-PAGE

Concentration

batch dependent

Buffer

Supplied in PBS,  PH7.5

Storage

Store at -20 °C for 12 months. Store at -80 °C for long term storage.

Shipping Condition

Shipped on ice packs.

Note

This product is for research use only.

Reactivity

Human

Reference

1. Azekawa S,  et al. BMJ Open Respir Res,  2023 May. PMID 37230764
2. de Haan A,  et al. Kidney Int,  2023 May. PMID 37085259
3. Lucarelli G,  et al. Int J Mol Sci,  2023 Mar 2. PMID 36902242