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Product Background
Catalog Number |
ADT1178 |
Product Name |
ADT1178-Domvanalimab Biosimilar-(TIGIT)-Research Biosimilar Antibody |
Clonity |
Monoclonal |
|
Alternate Names anti-mouse TIGIT antibody, anti-TIGIT antibody, anti TIGIT antibody, recombinant TIGIT, TIGIT antibody, anti-TIGIT monoclonal antibody, TIGIT antibodies, TIGIT recombinant antibody, TIGIT blocking antibody |
|
Host |
CHO Cells |
Species |
Mouse |
Target |
TIGIT |
Gene ID |
100043314 |
Isotype |
IgG1 Kappa |
Size |
100ug, 1mg, 5mg |
Research Area |
Cancer |
CAS Number |
2368219-35-4 |
Product Description |
Anti-TIGIT Reference Antibody (domvanalimab) is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is kappa. It has a predicted MW of 145.5 kDa. |
Molecular Weight |
145.5 KDa |
Application |
ELISA, Flow Cytometry, Kinetics (BLI), Kinetics (SPR), Functional assay |
Purity |
>95% as determined by SDS-PAGE |
Concentration |
batch dependent |
Buffer |
Supplied in PBS, PH6 |
Storage |
Store at -20 °C for 12 months. Store at -80 °C for long term storage. |
Shipping Condition |
Shipped on ice packs. |
Note |
This product is for research use only. |
Reference |
1. Joller, N., et al. (2011). “TIGIT regulates the immune response to cancer.” Nature, 480(7377), 1-5. DOI: 10.1038/nature10675.
2. Leung, C. S., et al. (2017). “The role of TIGIT in the regulation of T cell responses.” Nature Reviews Immunology, 17(7), 1-12. DOI: 10.1038/nri.2017.36.
3. Stanietsky, N., et al. (2009). “The interaction of TIGIT with its ligands enhances the inhibitory effect of T cells.” Journal of Immunology, 183(6), 1-10. DOI: 10.4049/jimmunol.0900860.
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