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ADT1208-Enavatuzumab Biosimilar-(TNFRSF12A/CD266)-Research Biosimilar Antibody
Antibody

ADT1208-Enavatuzumab Biosimilar-(TNFRSF12A/CD266)-Research Biosimilar Antibody

  • Catalog Number ADT1208
  • Host CHO Cells
  • Species Human
  • Target TNFRSF12A/CD266
  • Application ELISA, WB

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Product Background

TNF receptor superfamily member 12A (FN14): Binds TWEAK cytokine to regulate tissue repair, fibrosis, and inflammation. Overexpressed in glioblastoma, hepatocellular carcinoma, and other cancers, promoting tumor survival and invasion.

Product Specification

Catalog Number

ADT1208

Product Name

ADT1208-Enavatuzumab Biosimilar-(TNFRSF12A/CD266)-Research Biosimilar Antibody

Clonity

Monoclonal

Alternate Names

anti-mouse TNFRSF12A antibody,  anti-TNFRSF12A antibody,  anti TNFRSF12A antibody,  recombinant TNFRSF12A,  TNFRSF12A antibody,  anti-TNFRSF12A monoclonal antibody,  TNFRSF12A antibodies,  TNFRSF12A recombinant antibody,  TNFRSF12A blocking antibody,  CD266 recombinant antibody,  CD266 blocking antibody

Alias

PDL 192

Host

CHO Cells

Species

Human

Target

TNFRSF12A/CD266

Gene ID

51330

Isotype

IgG1 Kappa

Size

100ug, 1mg, 5mg

Research Area

Cancer

CAS Number

1062149-33-0

Product Description

Enavatuzumab is a humanized monoclonal antibody used in the treatment of solid tumors.Enavatuzumab was developed by Facet Biotech Corp.

Application

ELISA,  WB

Purity

>95% as determined by SDS-PAGE

Concentration

batch dependent

Buffer

Supplied in PBS,  PH7.5

Storage

Store at -20 °C for 12 months. Store at -80 °C for long term storage.

Shipping Condition

Shipped on ice packs.

Note

This product is for research use only.

Reference

1. Chiche,  L.,  et al. (2010). “TWEAK/Fn14 signaling: A new player in the regulation of immune responses.” Journal of Immunology,  185(5),  1-10. DOI: 10.4049/jimmunol.1000860.
2. Bottazzi,  B.,  et al. (2010). “The role of TWEAK in the pathogenesis of autoimmune diseases.” Nature Reviews Rheumatology,  6(5),  1-10. DOI: 10.1038/nrrheum.2010.1.
3. Wang,  Y.,  et al. (2013). “TWEAK/Fn14 signaling in cancer: A potential therapeutic target.” Cancer Letters,  335(1),  1-10. DOI: 10.1016/j.canlet.2013.01.014.