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ADT1222-Erlizumab Biosimilar-Anti-ITGB2/CD18 mAb-Research Grade
Antibody

ADT1222-Erlizumab Biosimilar-Anti-ITGB2/CD18 mAb-Research Grade

  • Catalog Number ADT1222
  • Host CHO Cells
  • Species Human
  • Target ITGB2/CD18
  • Application ELISA, WB

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Product Background

ITGB2 (Integrin Beta 2), also known as CD18, is a key subunit of the β2 integrin family, forming heterodimers with α subunits (CD11a, CD11b, CD11c, CD11d) to mediate leukocyte adhesion and migration. Structurally, CD18 contains an extracellular domain for ligand binding (e.g., ICAMs, fibrinogen), a transmembrane helix, and a cytoplasmic tail that interacts with cytoskeletal proteins (e.g., talin) and signaling molecules.

Product Specification

Catalog Number

ADT1222

Product Name

ADT1222-Erlizumab Biosimilar-Anti-ITGB2/CD18 mAb-Research Grade

Clonity

Monoclonal

Alternate Names

anti-mouse ITGB2 antibody,  anti-ITGB2 antibody,  anti ITGB2 antibody,  recombinant ITGB2,  ITGB2 antibody,  anti-ITGB2 monoclonal antibody,  ITGB2 antibodies,  ITGB2 recombinant antibody,  ITGB2 blocking antibody,  CD18 recombinant antibody,  CD18 blocking antibody

Alias

YFC51.1

Host

CHO Cells

Species

Human

Target

ITGB2/CD18

Gene ID

3689

Isotype

IgG1-nd

Size

1mg, 5mg

Research Area

Immunology

Application

ELISA,  WB

Purity

>95% as determined by SDS-PAGE

Concentration

batch dependent

Buffer

Supplied in PBS,  PH7.5

Storage

Store at -20 °C for 12 months. Store at -80 °C for long term storage.

Shipping Condition

Shipped on ice packs.

Note

This product is for research use only.

Reference

1. Conley HE,  et al. Biomolecules,  2023 May 26. PMID 37371473
2. Liu H,  et al. Front Endocrinol (Lausanne),  2022. PMID 36714574
3. Ma Q,  et al. Blood,  2022 Jun 9. PMID 35303071