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ADT1400-Mirikizumab Biosimilar-(IL23A)-Research Biosimilar Antibody
Antibody

ADT1400-Mirikizumab Biosimilar-(IL23A)-Research Biosimilar Antibody

  • Catalog Number ADT1400
  • Host CHO Cells
  • Species Human
  • Target IL23A
  • Application ELISA, WB

By maintaining stringent quality control throughout the production process, we provide blocking antibody that meet the highest standards of purity and performance, making them ideal for research applications.

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Product Background

IL23A is a gene encoding the p19 subunit of interleukin-23 (IL-23), a pro-inflammatory cytokine critical in immune responses. IL-23 is a heterodimer composed of IL23A (p19) and IL12B (p40), the latter shared with IL-12. This cytokine is pivotal in driving T helper 17 (Th17) cell responses, linking it to autoimmune diseases and chronic inflammation.

Product Specification

Catalog Number

ADT1400

Product Name

ADT1400-Mirikizumab Biosimilar-(IL23A)-Research Biosimilar Antibody

Clonity

Monoclonal

Alternate Names

anti-IL13a antibody,  anti IL13a antibody,  recombinant IL13a,  IL13a antibody,  anti-IL13a monoclonal antibody,  IL13a antibodies,  IL13a recombinant antibody,  IL13a blocking antibody

Alias

LY-3074828

Host

CHO Cells

Species

Human

Target

IL23A

Gene ID

51561

Isotype

IgG4 Kappa

Size

1mg, 5mg

Research Area

Immunology

CAS Number

1884201-71-1

Product Description

Mirikizumab (INN,  development code LY3074828) is a human monoclonal antibody designed for the treatment of psoriasis. This drug was developed by Eli Lilly and Co. As of 2018,  mirikizumab is undergoing Phase III trials.

Application

ELISA,  WB

Purity

>95% as determined by SDS-PAGE

Concentration

batch dependent

Buffer

Supplied in PBS,  PH7.5

Storage

Store at -20 °C for 12 months. Store at -80 °C for long term storage.

Shipping Condition

Shipped on ice packs.

Note

This product is for research use only.

Reference

1. Cua,  D. J.,  et al. (2003). “Interleukin-23 as a therapeutic target in autoimmune disease.” Nature Reviews Drug Discovery,  2(1),  1-12.
2. McGeachy,  M. J.,  et al. (2007). “The role of IL-23 in the development of Th17 cells.” Nature Reviews Immunology,  7(9),  657-667.
3. Korn,  T.,  et al. (2009). “IL-23 and IL-17 in the pathogenesis of autoimmune disease.” Nature Reviews Immunology,  9(9),  681-693.