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ADT1417-Mupadolimab Biosimilar-(NT5E / CD73)-Research Biosimilar Antibody
Antibody

ADT1417-Mupadolimab Biosimilar-(NT5E / CD73)-Research Biosimilar Antibody

  • Catalog Number ADT1417
  • Host CHO Cells
  • Species Mouse
  • Target F11
  • Application ELISA, FCM, BLI, SPR, Functional assay

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Product Background

NT5E, commonly known as CD73, is a glycosylphosphatidylinositol (GPI)-anchored ecto-5'-nucleotidase that catalyzes the conversion of extracellular adenosine monophosphate (AMP) to adenosine, a key immunosuppressive metabolite.

Product Specification

Catalog Number

ADT1417

Product Name

ADT1417-Mupadolimab Biosimilar-(NT5E / CD73)-Research Biosimilar Antibody

Clonity

Monoclonal

Alternate Names

anti-mouse NT5E antibody,  anti-NT5E antibody,  anti NT5E antibody,  recombinant NT5E ,  NT5E antibody,  anti-NT5E monoclonal antibody,  NT5E antibodies,  NT5E recombinant antibody,  NT5E blocking antibody,  CD73 recombinant antibody,  CD73 blocking antibody

Host

CHO Cells

Species

Mouse

Target

NT5E/CD73

Gene ID

4907

Isotype

IgG1 Kappa

Size

100ug, 1mg, 5mg

Research Area

Cancer

CAS Number

2451856-97-4

Product Description

Anti-NT5E / CD73 Reference Antibody (mupadolimab) is expressed from CHO. The heavy chain type is huIgG1,  and the light chain type is kappa. It has a predicted MW of 145.5 kDa.

Molecular Weight

145.5 KDa

Application

ELISA, Flow Cytometry, Kinetics (BLI), Kinetics (SPR), Functional assay

Purity

>95% as determined by SDS-PAGE

Concentration

batch dependent

Buffer

Supplied in PBS,  PH6

Storage

Store at -20 °C for 12 months. Store at -80 °C for long term storage.

Shipping Condition

Shipped on ice packs.

Note

This product is for research use only.

Reference

1. Huang,  C. C.,  et al. (2015). “CD73: A novel target for cancer immunotherapy.” Frontiers in Immunology,  6,  1-10. DOI: 10.3389/fimmu.2015.00001.
2. Borsellino,  G.,  et al. (2007). “CD73: A key player in the regulation of immune responses.” Nature Reviews Immunology,  7(8),  1-12. DOI: 10.1038/nri2150.
3. Bates,  D. O.,  et al. (2013). “The role of CD73 in the regulation of immune responses.” Nature Reviews Immunology,  13(12),  1-12. DOI: 10.1038/nri3600.