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ADT1435-Nerelimomab Biosimilar-Anti-TNFSF2/TNF-alpha/TNFA mAb-Research Grade
Antibody

ADT1435-Nerelimomab Biosimilar-Anti-TNFSF2/TNF-alpha/TNFA mAb-Research Grade

  • Catalog Number ADT1435
  • Host CHO Cells
  • Species Mouse
  • Target TNFSF2/TNF-alpha/TNFA
  • Application Functional assay, IF, Neut, ELISA, FC, IP, ICC

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Product Background

TNFA (TNF superfamily member 2, TNFSF2) is located on chromosome 6p21.3. TNF-α is synthesized as a 233-amino acid transmembrane precursor (tmTNF), cleaved by TACE/ADAM17 to release a 157-amino acid soluble homotrimer (sTNF). Binds to TNFR1 (ubiquitous, pro-apoptotic) and TNFR2 (immune/endothelial cells, pro-survival).

Product Specification

Catalog Number

ADT1435

Product Name

ADT1435-Nerelimomab Biosimilar-Anti-TNFSF2/TNF-alpha/TNFA mAb-Research Grade

Clonity

Monoclonal

Alternate Names

mouse tnf alpha,  anti tnf alpha,  tnf alpha monoclonal antibody,  human tnf alpha,  anti-tnfa antibody,  anti-tnfa antibody,  anti tnfa antibody,  recombinant tnfa,  tnfa antibody,  anti-tnfa monoclonal antibody,  tnfa antibodies,  tnfa recombinant antibody,  tnfa blocking antibody,  TNFSF2 recombinant antibody,  TNFSF2 blocking antibody

Alias

BAYX1351

Host

CHO Cells

Species

Mouse

Target

TNF alpha/TNFA/TNFSF2

Gene ID

21926

Isotype

IgG1

Size

1mg, 5mg

Research Area

Cancer

CAS Number

162774-06-3

Product Description

Nerelimomab is a mouse monoclonal antibody acting as a TNF Inhibitionitor.

Application

Functional assay,  IF,  Neut,  ELISA,  FC,  IP,  ICC

Purity

>95% as determined by SDS-PAGE

Concentration

batch dependent

Buffer

Supplied in PBS,  PH7.5

Storage

Store at -20 °C for 12 months. Store at -80 °C for long term storage.

Shipping Condition

Shipped on ice packs.

Note

This product is for research use only.

Reference

1. Queiroz-Junior CM,  et al. Life Sci,  2023 Jul 1. PMID 37142087
2. Li J,  et al. J Nutr Biochem,  2023 Jul. PMID 37085057
3. Shirakami Y,  et al. J Gastroenterol Hepatol,  2023 May. PMID 36890117