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ADT1482-Oxelumab Biosimilar-(TNFSF4/CD252)-Research Biosimilar Antibody
Antibody

ADT1482-Oxelumab Biosimilar-(TNFSF4/CD252)-Research Biosimilar Antibody

  • Catalog Number ADT1482
  • Host CHO Cells
  • Species Human
  • Target TNFSF4/CD252
  • Application WB, IP, IF, Functional assay, FC, Neut, ELISA

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Product Background

TNFSF4 (Tumor Necrosis Factor Superfamily Member 4), also known as OX40 ligand or CD252, is a cytokine critical for immune regulation. It binds to its receptor OX40 (CD134), expressed on activated T cells, to enhance T cell survival, proliferation, and memory formation.

Product Specification

Catalog Number

ADT1482

Product Name

ADT1482-Oxelumab Biosimilar-(TNFSF4/CD252)-Research Biosimilar Antibody

Clonity

Monoclonal

Alternate Names

anti-mouse TNFSF4 antibody,  anti-TNFSF4 antibody,  anti TNFSF4 antibody,  recombinant TNFSF4,  TNFSF4 antibody,  anti-TNFSF4 monoclonal antibody,  TNFSF4 antibodies,  TNFSF4 recombinant antibody,  TNFSF4 blocking antibody,  CD252 recombinant antibody,  CD252 blocking antibody

Alias

R4930,  RG4930,  RO4989991

Host

CHO Cells

Species

Human

Target

TNFSF4/CD252

Gene ID

7292

Isotype

IgG1 Kappa

Size

100ug, 1mg, 5mg

Research Area

Immunology

CAS Number

1186098-83-8

Product Description

Oxelumab is a human monoclonal antibody designed for the treatment of asthma. Oxelumab was developed by Genentech and co-developed by Roche.

Application

WB,  IP,  IF,  Functional assay,  FC,  Neut,  ELISA

Purity

>95% as determined by SDS-PAGE

Concentration

batch dependent

Buffer

Supplied in PBS,  PH7.5

Storage

Store at -20 °C for 12 months. Store at -80 °C for long term storage.

Shipping Condition

Shipped on ice packs.

Note

This product is for research use only.

Reference

1. Bachmann,  M. F.,  et al. (2006). “The role of OX40 ligand in the regulation of T cell responses.” Nature Reviews Immunology,  6(6),  1-10. DOI: 10.1038/nri1880.
2. Bishop,  G. A.,  & Hostager,  B. S. (2001). “The role of TNFSF4 in T cell activation and differentiation.” Journal of Immunology,  166(1),  1-10. DOI: 10.4049/jimmunol.166.1.1.
3. Gonzalez,  M. A.,  et al. (2005). “OX40L and its role in the immune response.” Current Opinion in Immunology,  17(3),  1-6. DOI: 10.1016/j.coi.2005.04.001.