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Product Background
Catalog Number |
ADT1504 |
Product Name |
ADT1504-Pidilizumab Biosimilar-Anti-PDCD1/CD279 mAb-Research Grade |
Alias |
CT-011 |
Clonity |
Monoclonal |
|
Alternate Names anti-mouse pd-1 antibody, anti-pd-1 antibody, anti pd-1 antibody, recombinant pd-1, pd-1 antibody, anti-pd-1 monoclonal antibody, pd-1 antibodies, pd-1 recombinant antibody, pd-1 blocking antibody, CD279 recombinant antibody, CD279 blocking antibody |
|
Host |
CHO Cells |
Species |
Human |
Target |
PDCD1/PD-1/CD279 |
Gene ID |
5133 |
Isotype |
IgG1 Kappa |
Size |
1mg, 5mg |
Research Area |
Cancer |
CAS Number |
1036730-42-3 |
Product Description |
Pidilizumab (formerly CT-011) is a monoclonal antibody being developed by Medivation for the treatment of cancer and infectious diseases. Pidilizumab was originally thought to bind to the PD-1 immune checkpoint molecule, however, recent evidence suggests that Delta-like 1 (DLL1) is its primary binding target while binding to PD-1 is secondary and restricted to non-glycosylated and hypoglycosylated forms of this molecule. |
Application |
ELISA, WB |
Purity |
>95% as determined by SDS-PAGE |
Concentration |
batch dependent |
Buffer |
Supplied in PBS, PH7.5 |
Storage |
Store at -20 °C for 12 months. Store at -80 °C for long term storage. |
Shipping Condition |
Shipped on ice packs. |
Note |
This product is for research use only. |
Reference |
1. Ma Y, et al. Zhonghua Yu Fang Yi Xue Za Zhi, 2023 Jun 6. PMID 37357205
2. Mirsharif ES, et al. Int Immunopharmacol, 2023 Jun. PMID 37172423
3. Tarique M, et al. Front Immunol, 2023. PMID 37153623
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