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Product Background
Catalog Number |
ADT1531 |
Product Name |
ADT1531-Ragifilimab Biosimilar-(TNFRSF18 / GITR / CD357)-Research Biosimilar Antibody |
Clonity |
Monoclonal |
|
Alternate Names anti-mouse TNFRSF18 antibody, anti-TNFRSF18 antibody, anti TNFRSF18 antibody, recombinant TNFRSF18 , TNFRSF18 antibody, anti-TNFRSF18 monoclonal antibody, TNFRSF18 antibodies, TNFRSF18 recombinant antibody, TNFRSF18 blocking antibody, GITR recombinant antibody, GITR blocking antibody, CD357 recombinant antibody, CD357 blocking antibody, |
|
Host |
CHO Cells |
Species |
Mouse |
Target |
TNFRSF18/GITR/CD357 |
Gene ID |
21936 |
Isotype |
IgG1 Kappa |
Size |
100ug, 1mg, 5mg |
Research Area |
Cancer |
CAS Number |
2207590-51-8 |
Product Description |
Anti-TNFRSF18 / GITR / CD357 Reference Antibody (ragifilimab) is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is kappa. It has a predicted MW of 145.5 kDa. |
Molecular Weight |
145.5 KDa |
Application |
ELISA, Flow Cytometry, Kinetics (BLI), Kinetics (SPR), Functional assay |
Purity |
>95% as determined by SDS-PAGE |
Concentration |
batch dependent |
Buffer |
Supplied in PBS, PH6 |
Storage |
Store at -20 °C for 12 months. Store at -80 °C for long term storage. |
Shipping Condition |
Shipped on ice packs. |
Note |
This product is for research use only. |
Reference |
1. Takahashi, T., et al. (2000). “GITR: A new member of the TNF receptor superfamily that regulates T cell activation.” Journal of Immunology, 164(12), 1-7. DOI: 10.4049/jimmunol.164.12.6100.
2. Shimizu, J., et al. (2002). “GITR signaling enhances the survival of T cells.” Journal of Immunology, 169(1), 1-7. DOI: 10.4049/jimmunol.169.1.1.
3. Kurtulus, S., et al. (2015). “The role of GITR in cancer immunotherapy.” Nature Reviews Immunology, 15(1), 1-10. DOI: 10.1038/nri.2014.139.
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