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ADT1547-Retifanlimab Biosimilar-Anti-PDCD1/PD1/CD279 mAb-Research Grade
Antibody

ADT1547-Retifanlimab Biosimilar-Anti-PDCD1/PD1/CD279 mAb-Research Grade

  • Catalog Number ADT1547
  • Host CHO Cells
  • Species Human
  • Target TNF alpha/TNFA/TNFSF2
  • Application ELISA, WB

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Product Background

The PD-1 gene, also known as PDCD1 (Programmed Cell Death 1), encodes a protein that plays a crucial role in regulating the immune system. Located on chromosome 2q37.3, PD-1 is primarily expressed on activated T cells, B cells, and some myeloid cells. The PD-1 protein is a member of the CD28 superfamily and functions as an immune checkpoint, which is essential for maintaining immune homeostasis and preventing autoimmunity.

Product Specification

Catalog Number

ADT1547

Product Name

ADT1547-Retifanlimab Biosimilar-Anti-PDCD1/PD1/CD279 mAb-Research Grade

Alias

INCMGA-00012,  MGA-012

Clonity

Monoclonal

Alternate Names

anti-mouse pd-1 antibody,  anti-pd-1 antibody,  anti pd-1 antibody,  recombinant pd-1,  pd-1 antibody,  anti-pd-1 monoclonal antibody,  pd-1 antibodies,  pd-1 recombinant antibody,  pd-1 blocking antibody, CD279 recombinant antibody,  CD279 blocking antibody

Host

CHO Cells

Species

Human

Target

PDCD1/PD-1/CD279

Gene ID

5133

Isotype

IgG4 Kappa

Size

100ug, 1mg, 5mg

Research Area

Cancer

CAS Number

2079108-44-2

Application

ELISA, WB

Purity

>95% as determined by SDS-PAGE

Concentration

batch dependent

Buffer

Supplied in PBS,  PH7.5

Storage

Store at -20 °C for 12 months. Store at -80 °C for long term storage.

Shipping Condition

Shipped on ice packs.

Note

This product is for research use only.

Reference

1. Ma Y,  et al. Zhonghua Yu Fang Yi Xue Za Zhi,  2023 Jun 6. PMID 37357205
2. Mirsharif ES,  et al. Int Immunopharmacol,  2023 Jun. PMID 37172423
3. Tarique M,  et al. Front Immunol,  2023. PMID 37153623