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ADT1575-Sasanlimab Biosimilar-Anti-PDCD1/PD1/CD279 mAb-Research Grade
Antibody

ADT1575-Sasanlimab Biosimilar-Anti-PDCD1/PD1/CD279 mAb-Research Grade

  • Catalog Number ADT1575
  • Host CHO Cells
  • Species Human
  • Target TNFRSF10A/CD261
  • Application ELISA, WB

Alpha Lifetech conducts comprehensive immunogenicity and stability testing on all of our biosimilar antibodies.

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Product Background

The PD-1 protein consists of an extracellular domain, a single transmembrane domain, and a cytoplasmic tail. The extracellular domain contains two immunoglobulin-like domains that facilitate its interaction with its ligands, PD-L1 and PD-L2. Upon binding to these ligands, PD-1 transmits inhibitory signals that reduce T cell activation, proliferation, and cytokine production, thereby modulating the immune response.

Product Specification

Catalog Number

ADT1575

Product Name

ADT1575-Sasanlimab Biosimilar-Anti-PDCD1/PD1/CD279 mAb-Research Grade

Alias

PF-06801591

Clonity

Monoclonal

Alternate Names

anti-mouse pd-1 antibody,  anti-pd-1 antibody,  anti pd-1 antibody,  recombinant pd-1,  pd-1 antibody,  anti-pd-1 monoclonal antibody,  pd-1 antibodies,  pd-1 recombinant antibody,  pd-1 blocking antibody, CD279 recombinant antibody,  CD279 blocking antibody

Host

CHO Cells

Species

Human

Target

PDCD1/PD-1/CD279

Gene ID

5133

Isotype

IgG4 Kappa

Size

100ug, 1mg, 5mg

Research Area

Cancer

CAS Number

2206792-50-7

Application

ELISA, WB

Purity

>95% as determined by SDS-PAGE

Concentration

batch dependent

Buffer

Supplied in PBS,  PH7.5

Storage

Store at -20 °C for 12 months. Store at -80 °C for long term storage.

Shipping Condition

Shipped on ice packs.

Note

This product is for research use only.

Reference

1. Ma Y,  et al. Zhonghua Yu Fang Yi Xue Za Zhi,  2023 Jun 6. PMID 37357205
2. Mirsharif ES,  et al. Int Immunopharmacol,  2023 Jun. PMID 37172423
3. Tarique M,  et al. Front Immunol,  2023. PMID 37153623