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ADT1584-Setoxaximab Biosimilar-(Stx2/SLT-II[Escherichia coli])-Research Biosimilar Antibody
Antibody

ADT1584-Setoxaximab Biosimilar-(Stx2/SLT-II[Escherichia coli])-Research Biosimilar Antibody

  • Catalog Number ADT1584
  • Host CHO Cells
  • Species Mouse
  • Target IL17A
  • Application FC, IP, ELISA, Neut, Functional assay, IF, ICC

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Product Background

Stx2 is a member of the Shiga toxin family, which includes Stx1 and Stx2 subtypes (e.g., Stx2a, Stx2c, Stx2d). Stx2 is more potent than Stx1 and is strongly associated with severe human disease.

Product Specification

Catalog Number

ADT1584

Product Name

ADT1584-Setoxaximab Biosimilar-(Stx2/SLT-II[Escherichia coli])-Research Biosimilar Antibody

Clonity

Monoclonal

Alternate Names

anti-mouse Stx2 antibody,  anti-Stx2 antibody,  anti Stx2 antibody,  recombinant Stx2,  Stx2 antibody,  anti-Stx2 monoclonal antibody,  Stx2 antibodies,  Stx2 recombinant antibody,  Stx2 blocking antibody,  SLT-II recombinant antibody,  SLT-II blocking antibody

Alias

Shigamabs-(drug name for the combination of pritoxaximab and setoxaximab),  caStx2

Host

Escherichia coli

Species

Mouse

Target

Stx2/SLT-II

Gene ID

13852

Isotype

IgG1 Kappa

Size

100ug, 1mg, 5mg

Research Area

Immunology

CAS Number

1351470-17-1

Application

FC,  IP,  ELISA,  Neut,  Functional assay,  IF,  ICC

Purity

>95% as determined by SDS-PAGE

Concentration

batch dependent

Buffer

Supplied in PBS,  PH7.5

Storage

Store at -20 °C for 12 months. Store at -80 °C for long term storage.

Shipping Condition

Shipped on ice packs.

Note

This product is for research use only.

Reference

1. Kang F,  et al. Nat Commun,  2022 Oct 31. PMID 36316316
2. Wang YX,  et al. Life Sci,  2020 Dec 15. PMID 33075373
3. Wang Y,  et al. Cell Death Dis,  2018 May 31. PMID 29855462