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Product Background
Catalog Number |
ADT1586 |
Product Name |
ADT1586-Sevirumab Biosimilar-Anti-HCMV mAb-Research Grade |
Alternate Names |
anti-mouse HCMV antibody, anti-HCMV antibody, anti HCMV antibody, recombinant HCMV, HCMV antibody, anti-HCMV monoclonal antibody, HCMV antibodies, HCMV recombinant antibody, HCMV blocking antibody |
Alias |
EV2 7, MSL 109, SDZ MSL 109
|
Clonity |
Monoclonal |
Host |
CHO Cells |
Species |
Human |
Target |
HCMV |
Isotype |
IgG1 Lambda |
Size |
1mg, 5mg |
Research Area |
Immunology |
Mechanism of Action |
Sevirumab is a monoclonal antibody targeting specific tumor-associated antigens or immune checkpoints. |
Metabolism |
Sevirumab has a long half-life and is distributed throughout the bloodstream and tissues. |
Application |
WB, IF, IP, Neut, Functional assay, ELISA, FC |
Purity |
>95% as determined by SDS-PAGE |
Concentration |
batch dependent |
Buffer |
Supplied in PBS, PH7.5 |
Storage |
Store at -20 °C for 12 months. Store at -80 °C for long term storage. |
Shipping Condition |
Shipped on ice packs. |
Note |
This product is for research use only. |
Reactivity |
Human |
|
Reference 1. Spector SA, et al. Advances in the understanding of human cytomegalovirus pathogenesis and its impact on human health. Journal of Clinical Virology. 2020 Jun;127:104362. PMID 32380045
2. Nelson CS, et al. Human cytomegalovirus: A comprehensive review of molecular mechanisms and clinical implications. Virology Journal. 2019 Dec 16;16(1):138. PMID 31871616
3. Dollard SC, et al. HCMV and its role in congenital and postnatal infections: Current perspectives and future directions. Clinical Microbiology Reviews. 2021 Jan;34(1)
. PMID 33127123
|