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Product Background
Catalog Number |
ADT1617 |
Product Name |
ADT1617-Tacatuzumab Biosimilar-Anti-Alpha-fetoprotein mAb-Research Grade |
|
Alternate Names anti-mouse AFP antibody, anti-AFP antibody, anti AFP antibody, recombinant AFP, AFP antibody, anti-AFP monoclonal antibody, AFP antibodies, AFP recombinant antibody, AFP blocking antibody |
|
Alias |
hAFP-31 |
Clonity |
Monoclonal |
Host |
CHO Cells |
Species |
Human |
Target |
AFP |
Gene ID |
174 |
Isotype |
IgG1 Kappa |
Size |
1mg, 5mg |
Research Area |
Cancer |
CAS Number |
476413-07-7 |
Product Description |
Yttrium (90Y) tacatuzumab tetraxetan (trade name AFP-Cide) is a humanized monoclonal antibody intended for the treatment of cancer. The antibody itself, tacatuzumab, is conjugated with tetraxetan, a chelator for yttrium-90, a radioisotope which destroys the tumour cells. |
Molecular Weight |
Tacatuzumab is a monoclonal antibody targeting specific tumor-associated antigens. |
Metabolism |
Tacatuzumab has a long half-life and is distributed throughout the bloodstream and tissues. |
Application |
IF, IP, Neut, Functional assay, ELISA, FC, WB |
Purity |
>95% as determined by SDS-PAGE |
Concentration |
batch dependent |
Buffer |
Supplied in PBS, PH7.5 |
Storage |
Store at -20 °C for 12 months. Store at -80 °C for long term storage. |
Shipping Condition |
Shipped on ice packs. |
Note |
This product is for research use only. |
Reactivity |
Human |
|
Reference 1.Xu Y, et al. Cancer Lett, 2023 Jul 10. PMID 37217071
2.Zhang M, et al. Front Immunol, 2023. PMID 36911723
3.Munson PV, et al. Cancer Res, 2023 May 2. PMID 36847613
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