ADT1648-Tigatuzumab Biosimilar-Anti-TNFRSF10B/CD262 mAb-Research Grade
- +1 609-736-0910
- info@alphalifetech.com
- 90 State Street, STE 700 Office 40, Albany, NY 12207 United States
Product Background
Catalog Number |
ADT1648 |
Product Name |
ADT1648-Tigatuzumab Biosimilar-Anti-TNFRSF10B/CD262 mAb-Research Grade |
Clonity |
Monoclonal |
|
Alternate Names TNFRSF10B antibody, CD262 antibody, cd262 mouse, anti-mouse CD262 antibody, anti-CD262 antibody, anti CD262 antibody, recombinant CD262, anti-CD262 monoclonal antibody, CD262 antibodies, CD262 recombinant antibody, CD262 blocking antibody, TNFRSF10B recombinant antibody, TNFRSF10B blocking antibody |
|
Alias |
CS-1008, TRA-8
|
Host |
CHO Cells |
Species |
Human |
Target |
TNFRSF10B/CD262 |
Gene ID |
8795 |
Isotype |
IgG1 |
Size |
100ug, 1mg, 5mg |
Research Area |
Cancer |
CAS Number |
918127-53-4 |
Product Description |
Tigatuzumab (CS-1008) is a monoclonal antibod for the treatment of cancer. As of October 2009, a clinical trial for the treatment of pancreatic cancer, Phase II trials for colorectal cancer, non-small cell lung cancer, and ovarian cancer have been completed. |
Mechanism of Action |
Tigatuzumab is a monoclonal antibody targeting specific tumor-associated antigens or immune checkpoint proteins.
|
Metabolism |
Tigatuzumab has a long half-life and is distributed throughout the bloodstream and tissues. |
Application |
IF, IP, Neut, Functional assay, ELISA, FC |
Purity |
>95% as determined by SDS-PAGE |
Concentration |
batch dependent |
Buffer |
Supplied in PBS, PH7.5 |
Storage |
Store at -20 °C for 12 months. Store at -80 °C for long term storage. |
Shipping Condition |
Shipped on ice packs. |
Note |
This product is for research use only. |
Reactivity |
Human |
Reference |
1. Mora-Molina R, et al. Int J Mol Sci, 2022 Aug 12. PMID 36012252
2. Qin J, et al. Expert Rev Respir Med, 2022 Jul. PMID 35822538
3. Sullivan GP, et al. Dev Cell, 2020 Mar 23. PMID 32109381
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