Antibody
ADT1653-Timigutuzumab Biosimilar-Anti-ERBB2/EGFR2/CD340 mAb-Research Grade
0102030405
- +1 609-736-0910
- info@alphalifetech.com
- 90 State Street, STE 700 Office 40, Albany, NY 12207 United States
Product Background
ERBB2 (Human Epidermal Growth Factor Receptor 2), also known as HER2, is a transmembrane receptor tyrosine kinase belonging to the EGFR/ERBB family. Its structure includes: extracellular domain-binds to other ERBB family members (e.g., HER3, EGFR) but lacks a known ligand, transmembrane domain-anchors the receptor in the cell membrane, and intracellular tyrosine kinase domain-activates downstream signaling upon dimerization.
Catalog Number |
ADT1653 |
Product Name |
ADT1653-Timigutuzumab Biosimilar-Anti-ERBB2/EGFR2/CD340 mAb-Research Grade |
Alternate Names |
recombinant erbb2, ErbB2 monoclonal antibody, human erbb2, erbb2 antibody, mouse erbb2, anti-mouse erbb2 antibody, anti-erbb2 antibody, anti erbb2 antibody, recombinant cd340, cd340 antibody, anti-erbb2 monoclonal antibody, egfr2 antibodies, erbb2 recombinant antibody, erbb2 blocking antibody, CD340 recombinant antibody, CD340 blocking antibody |
Alias |
GEXMab73, GT-MAb7.3-GEX, TrastuzuMab-GEX |
Clonity |
Monoclonal |
Host |
CHO Cells |
Species |
Human |
Target |
ERBB2/EGFR2/CD340 |
Gene ID |
2064 |
Isotype |
IgG1 Kappa |
Size |
100ug, 1mg, 5mg |
Research Area |
Immunology |
CAS Number |
1665274-14-5 |
Application |
ELISA, IHC, IF, IP, Flow Cytometry, Functional assay |
Purity |
>95% as determined by SDS-PAGE |
Concentration |
batch dependent |
Buffer |
Supplied in PBS, PH7.5 |
Storage |
Store at -20 °C for 12 months. Store at -80 °C for long term storage. |
Shipping Condition |
Shipped on ice packs. |
Note |
This product is for research use only. |
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Reference 1. Saeed Z, et al. J Ayub Med Coll Abbottabad, 2023 Apr-Jun. PMID 37422821
2. Uckun FM, et al. Int J Mol Sci, 2023 Jun 9. PMID 37373090
3. Lee SY, et al. Breast Cancer Res Treat, 2023 Jul. PMID 37184775
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