ADT1673-Trevogrumab Biosimilar-(MSTN/GDF8)-Research Biosimilar Antibody
- +1 609-736-0910
- info@alphalifetech.com
- 90 State Street, STE 700 Office 40, Albany, NY 12207 United States
Product Background
Catalog Number |
ADT1673 |
Product Name |
ADT1673-Trevogrumab Biosimilar-(MSTN/GDF8)-Research Biosimilar Antibody |
Clonity |
Monoclonal |
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Alternate Names anti-mouse MSTN antibody, anti-MSTN antibody, anti MSTN antibody, recombinant MSTN, MSTN antibody, anti-MSTN monoclonal antibody, MSTN antibodies, MSTN recombinant antibody, MSTN blocking antibody, GDF8 recombinant antibody, GDF8 blocking antibody |
|
Alias |
REGN-1033, REGN1033, SAR-391786 |
Host |
CHO Cells |
Species |
Human |
Target |
MSTN/GDF8 |
Gene ID |
2660 |
Isotype |
IgG4 Kappa |
Size |
100ug, 1mg, 5mg |
Research Area |
Immunology |
CAS Number |
1429201-24-0 |
Product Description |
Trevogrumab (INN, development code REGN1033) is a human monoclonal antibody designed for the treatment of muscle atrophy due to orthopedic disuse and sarcopenia. |
Application |
ELISA, WB |
Purity |
>95% as determined by SDS-PAGE |
Concentration |
batch dependent |
Buffer |
Supplied in PBS, PH7.5 |
Storage |
Store at -20 °C for 12 months. Store at -80 °C for long term storage. |
Shipping Condition |
Shipped on ice packs. |
Note |
This product is for research use only. |
Reference |
1. Sartori, R., et al. (2013). “Myostatin regulates the expression of muscle-specific microRNAs.” The Journal of Biological Chemistry, 288(12), 1-8. DOI: 10.1074/jbc.M112.433123.
2. Harris, M. P., et al. (2015). “Myostatin and its role in muscle regeneration.” Nature Reviews Molecular Cell Biology, 16(10), 1-12. DOI: 10.1038/nrm.2015.10.
3. Dyer, C. A., et al. (2016). “Myostatin: A potential therapeutic target for muscle wasting.” Current Opinion in Pharmacology, 27, 1-6. DOI: 10.1016/j.coph.2016.01.002.
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