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ADT1683-Urtoxazumab Biosimilar-Anti-Stx-2/SLT-II mAb-Research Grade
Antibody

ADT1683-Urtoxazumab Biosimilar-Anti-Stx-2/SLT-II mAb-Research Grade

  • Catalog Number ADT1683
  • Host CHO Cells
  • Species Human
  • Target VEGFA/ANGPT2
  • Application WB, Functional assay, IF, Neut, ELISA, FC, IP

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Product Background

Stx2 is a member of the Shiga toxin family, which includes Stx1 and Stx2 subtypes (e.g., Stx2a, Stx2c, Stx2d). Stx2 is more potent than Stx1 and is strongly associated with severe human disease.

Product Specification

Catalog Number

ADT1683

Product Name

ADT1683-Urtoxazumab Biosimilar-Anti-Stx-2/SLT-II mAb-Research Grade

Clonity

Monoclonal

Alternate Names

anti-mouse Stx-2 antibody,  anti-Stx-2 antibody,  anti Stx-2 antibody,  recombinant Stx-2,  Stx-2 antibody,  anti-Stx-2 monoclonal antibody,  Stx-2 antibodies,  Stx-2 recombinant antibody,  Stx-2 blocking antibody,  SLT-II recombinant antibody,  SLT-II blocking antibody

Alias

HuVTm1.1,  TMA-15

Host

Escherichia coli

Species

Human

Target

Stx2/SLT-II

Gene ID

2054

Isotype

IgG1 Kappa

Size

1mg, 5mg

Research Area

Immunology

CAS Number

502496-16-4

Product Description

Urtoxazumab is a humanized monoclonal antibody against diarrhoea caused by Escherichia coli,  serotype O121. The drug is designed to bind to a toxin of this bacterium,  so that it can be more easily broken down and eliminated from the body.

Mechanism of Action

Urtoxazumab is a monoclonal antibody targeting specific tumor-associated antigens or immune checkpoints.

Metabolism

Urtoxazumab has a long half-life and is distributed throughout the bloodstream and tissues.

Application

WB,  Functional assay,  IF,  Neut,  ELISA,  FC,  IP

Purity

>95% as determined by SDS-PAGE

Concentration

batch dependent

Buffer

Supplied in PBS,  PH7.5

Storage

Store at -20 °C for 12 months. Store at -80 °C for long term storage.

Shipping Condition

Shipped on ice packs.

Note

This product is for research use only.

Reactivity

Human

Reference

1. Kang F,  et al. Nat Commun,  2022 Oct 31. PMID 36316316
2. Wang YX,  et al. Life Sci,  2020 Dec 15. PMID 33075373
3. Wang Y,  et al. Cell Death Dis,  2018 May 31. PMID 29855462