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ADT1717-Zagotenemab Biosimilar-(MAPT)-Research Biosimilar Antibody
Antibody

ADT1717-Zagotenemab Biosimilar-(MAPT)-Research Biosimilar Antibody

  • Catalog Number ADT1717
  • Host CHO Cells
  • Species Human
  • Target MAPT
  • Application ELISA, WB

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Product Background

MAPT is located on chromosome 17q21.31 and undergoes complex alternative splicing, producing six major isoforms in the human central nervous system.

Product Specification

Catalog Number

ADT1717

Product Name

ADT1717-Zagotenemab Biosimilar-(MAPT)-Research Biosimilar Antibody

Clonity

Monoclonal

Alternate Names

anti-mapt antibody,  anti mapt antibody,  recombinant mapt,  mapt antibody,  anti-mapt monoclonal antibody,  mapt antibodies,  mapt recombinant antibody,  mapt blocking antibody

Alias

LY-3303560

Host

CHO Cells

Species

Human

Target

MAPT

Gene ID

4137

Isotype

IgG4 Kappa

Size

100ug, 1mg, 5mg

Research Area

Neurobiology

CAS Number

2019133-28-7

Product Description

Zagotenemab is under investigation in clinical trial NCT03518073 (A Study of LY3303560 in Participants With Early Symptomatic Alzheimer's Disease).

Application

ELISA,  WB

Purity

>95% as determined by SDS-PAGE

Concentration

batch dependent

Buffer

Supplied in PBS,  PH7.5

Storage

Store at -20 °C for 12 months. Store at -80 °C for long term storage.

Shipping Condition

Shipped on ice packs.

Note

This product is for research use only.

Reference

1. Wang,  Y.,  & Mandelkow,  E. (2016). “Tau in physiology and pathology.” Nature Reviews Neuroscience,  17(1),  1-14.
2. Kfoury,  N.,  & Holmes,  B. B. (2016). “Tau propagation in a model of Alzheimer’s disease.” Nature,  523(7561),  1-5.
3. Zhang,  Y.,  et al. (2019). “The role of tau in neurodegenerative diseases.” Nature Reviews Neuroscience,  20(1),  1-14.