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AFP113-Tirzepatide
Isotype Control Antibodies

AFP113-Tirzepatide

  • Catalog Number AFP113
  • Molecular Formula C₂₂₅H₃₄₈N₄₈O₆₈
  • Purity >98%
  • Purification HPLC
  • Endotoxin < 5 EU/mg

Tirzepatide is a first-in-class, unimolecular dual agonist of both the glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors. The molecule is a 39-amino acid synthetic peptide based on the GIP sequence, modified with a C20 fatty diacid moiety to enable weekly dosing through albumin binding. By simultaneously activating two distinct incretin pathways, Tirzepatide achieves a synergistic effect on insulin secretion, glucagon suppression, and energy balance that exceeds the impact of selective GLP-1 agonists.

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Product Background

The dual-receptor pharmacology of Tirzepatide is particularly effective for weight loss due to its integrated action on the brain and adipose tissue. While the GLP-1 component drives satiety and delays gastric emptying, the GIP component is thought to enhance insulin sensitivity and potentially modulate lipid metabolism within white adipose tissue. This multifaceted approach leads to significant improvements in metabolic health, providing a comprehensive strategy for managing obesity and Type 2 diabetes.

Product Specification

Catalog Number

AFP113

Product Name

AFP113-Tirzepatide

Molecular Formula

C₂₂₅H₃₄₈N₄₈O₆₈

Molecular Weight

4813.53 Da

Structural formula

Y-Aib-Q-G-T-F-T-S-N-Y-S-I-amL-L-N-K(K17[AEEA-AEEA-γGlu-
GGSGGGSGGSGGRLIEDICLPRWGCLWEDD])-A-Q-Aib-A-F-I-E-Y-L-L-E-G-G-P-S-S-G-A-P-P-P-S-NH2

CAS Accession

2023788-19-2

Size

1mg, 5mg, 100mg, bulk

Storage Condition

Cool dry place(-20±5℃,Keep away from acids and alkali)

Purity

>98%

Purification

HPLC

Endotoxin

< 5 EU/mg

Reconstitution Conditions

Reconstitute in ddH₂O for a stock solution.

Shipping Condition

This product is shipped on ice packs.

Note

For Research Use Only!