Ratonga Whakamaemae Pūmua Kiriuhi

Kua angitu a Alpha Lifetech ki te whakarite i ngā mano tini o ngā pūmua recombinant mā ā mātou kiritaki, tae atu ki ngā paturopi recombinant, ngā pūmua huna, ngā pūmua transmembrane, ngā proteases, me ētahi atu, me ngā reiti angitu teitei. Me whakarato noa e ngā kiritaki he raupapa pūmua, he CDS, he ingoa pūmua rānei, ā, ka taea e Alpha Lifetech te whakawhanake i tētahi mahere whakaputa me te purenga pūmua hanumi katoa i roto i te wā poto ake. Ka taea e mātou te whakarato ratonga whakaputa pūmua ritenga i runga i ngā pūnaha whakaputa matua e whā, me te whiriwhiri i ngā rautaki whakaputa me te purenga pūmua hanumi rerekē i runga i ngā hiahia o te kiritaki.

He maha ngā taputapu me ngā taputapu purenga pūmua a Alpha Lifetech, e taea ai te whakarato ratonga purenga pūmua taiao me te purenga pūmua recombinant, pērā i te purenga hononga, te chromatography sieve ngota, te chromatography whakawhiti katote, me te chromatography hydrophobic. Ka whiriwhiria e mātou ngā tikanga purenga kia rite ki ngā hiahia motuhake o ā mātou kiritaki, ā, ka whakakotahi i ēnei ki tā mātou tūāpapa purenga pūmua hei whiwhi hua pūmua kounga teitei i roto i te wā poto.

Te Whakarōpūtanga o ngā Pūmua Kiriuhi

E ai ki te tohatoha o ngā pūmua i roto i te kiriuhi me te whanaungatanga i waenga i ngā pūmua kiriuhi me ngā ngako kiriuhi, ka wehea ngā pūmua kiriuhi kia toru ngā wāhanga, tae atu ki ngā pūmua kiriuhi taha, ngā pūmua kiriuhi whakauru, me ngā pūmua punga ngako.

Pūmua hongere ioni

Ko te pūmua hongere ionic he pūmua kiriuhi whakauru e whakauru ana ki roto i ngā kiriuhi koiora hei hanga i ngā hanganga hongere motuhake, e āhei ana ki te kawe i ētahi iona puta noa i ngā kiriuhi i roto, i waho hoki o te pūtau, me te ārai i ētahi atu iona kia haere. He mea nui te whiriwhiringa o ngā pūmua hongere ionic hei pupuri i ngā mahi ora pūtau pēnei i te rerekētanga o te kukū iona i waenga i roto, i waho hoki o te pūtau, te kawe i ngā neurotransmitter, me ētahi atu.

Ngā kaiwhakawhiwhi hononga pūmua G

Ko ngā kaiwhakawhiwhi hononga pūmua G he kupu whānui mō tētahi akomanga nui o ngā kaiwhakawhiwhi pūmua kiriuhi, koinei ngā kaiwhakawhiwhi mata pūtau maha rawa atu i roto i ngā eukaryote. Ko te mahi matua a ngā kaiwhakawhiwhi hononga pūmua G ko te tuku i ngā mōhiohio o waho o te pūtau ki roto o ngā pūtau mā te taunekeneke ki te pūmua G, he mahi nui tēnei i roto i te tuku tohu. Ka mōhio ngā kaiwhakawhiwhi hononga pūmua G ki ngā ligands o waho o te pūtau hei whakaoho i ngā ara tohu o roto o te pūtau, ā, mā reira ka whakahaere i ngā mahi ā-tinana o ngā pūtau.

Ngā Matūriki Pērā i te Huaketo

Ko te matūriki rite ki te huaketo he matūriki pūmua i hangaia mā te whakakotahitanga o tētahi, neke atu rānei o ngā pūmua hanganga o te huaketo. He rite te āhua me te hanganga o ēnei matūriki ki ngā matūriki huaketo tūturu, engari kāore i roto i a rātou te rauemi ira o te huaketo, nō reira kāore e pangia e te mate.

Ka taea e ngā Matūriki Pērā i te Huaketo te mahi hei tūāpapa whakaatu mō ngā pūmua kiriuhi, e whakatauira ana i te āhua me te mahi a ngā pūmua kiriuhi i roto i ngā taiao tūturu mā te whakaatu i ngā pūmua kiriuhi motuhake ki runga i ngā Matūriki Pērā i te Huaketo. I roto i te whakawhanaketanga kano kano, ka taea te whakaatu i ngā antigens tiaki o te huaketo, ko ngā pūmua kiriuhi te nuinga, ki runga i ngā Matūriki Pērā i te Huaketo hei whakaoho i te tinana ki te whakaputa urupare ārai mate ki ēnei antigens. He tino haumaru, he ārai mate hoki ngā kano kano i whakaritea mā tēnei tikanga.

Te Whakamaemaetanga o ngā Pūmua Kiriuhi

He maha ngā tikanga mō te purenga o ngā pūmua membrane, tae atu ki te chromatography hononga e whakamahi ana i te hononga o ngā pūmua membrane, i ngā tohu hanumi rānei, pērā i ngā tohu His, me ō rātou ligands motuhake hei whakatutuki i te purenga me te wehenga o ngā pūmua membrane. Ka whakamahia e te chromatography whakawhiti katote ngā āhuatanga utu o ngā pūmua membrane hei wehe i a rātou i runga i ngā kapia whakawhiti katote. Heoi, he maha ngā wā kei roto i ngā otinga pūmua membrane he hopi horoi, ā, ko te tango atu ka pā ki te whai huatanga o te chromatography whakawhiti katote. Ko te chromatography tātari gel he whakamahi i te rerekētanga o te taumaha ngota pūmua membrane hei wehe i runga i te pou gel, mā tēnei tikanga ka taea e tātou te whiwhi pūmua membrane parakore teitei. Nā te hononga me te hydrophobicity o ngā pūmua membrane, ka taea te wehe i a rātou i runga i ngā pou chromatography. He pai, he tere, he tino tairongo hoki tēnei tikanga, engari he nui hoki te utu.

te purenga pūmua kiriuhi-Alpha Lifetech

Pikitia 1 Kauwhata matua o te purenga hononga pūmua

Ngā painga o te purenga pūmua kiriuhiHE AHA koe i whiriwhiri ai

Te arotautanga o te kōtona

Ka taea te whakamana i te whakaaturanga pūmua wairewa teitei me te ngohe pūmua teitei

Ngā momo whakapūkara pūmua tauine maha: tauine iti (1L, 10L, me te 30L), tauine nui (80L, 130L, 250L, me te 500L ngā tāke whakapūkara)

Te whakarite i ngā pūmua recombinant parakore-teitei i roto i ngā mirikaramu me ngā karamu i roto i te wā poto

Iti te endotoxin: Tikanga kimi LAL

Mā te pūnaha tautoko tuhinga GMP katoa ka taea te whai i ngā rauemi katoa, ngā matū, me ngā mōhiohio whakarite mō te hua.

Hoki atu ki te Whārangi Pūtake Pūmua Membrane

Mena he pātai āu, tēnā whakapā mai ki a mātou i ngā wā katoa.

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