Peptide Library Screening Platform
Alpha Lifetech offers customized premade peptide library screening of proteins, cells, and tissue samples.
Request QuotePeptide Library Screening Platform
Alpha Lifetech possesses extensive expertise in peptide phage display library construction and screening, offering robust technical support for small molecule drug discovery, clinical diagnostics, disease therapeutics, and fundamental biological research. Backed by a team of seasoned scientists, we deliver high-quality peptide phage library construction and screening services tailored to help clients identify peptide candidates that precisely meet their target requirements. With over a decade of focused experience, we specialize in generating peptide sequences with high affinity and high specificity.
To further validate the functional and translational potential of these candidates, we provide comprehensive characterization services—including SPR, BLI, and flow cytometry-based assays—ensuring the reliability and clinical applicability of every peptide we deliver. To help clients reduce costs and accelerate their research timelines, we offer pre-constructed peptide libraries ready for immediate use. We also accept custom library construction services tailored to specific research needs—please visit our dedicated page (Learn More) for more information.
peptide library types
Alpha Lifetech is dedicated to developing peptide display library construction and screening programs for global customers, ensuring timely screening of functionally important peptide sequences. Our capabilities span linear peptide libraries (5-25 amino acids), cyclic peptide libraries, and randomized peptide libraries, with phage display libraries exceeding 109 diversity, enabling efficient identification of ideal sequences.
Diversified phage peptide library
Our libraries covers linear, cyclic, and modified peptides, ensuring broad target coverage and structural diversity. We have constructed over 10 specialized libraries—including linear 7-, 9-, 10-, 12-, and 15-mer peptides, as well as cyclic 7- and 12-mer peptides—to address the unique requirements of drug discovery, diagnostic marker identification, and functional peptide research.
Customized & Efficient Screening Process
We tailor screening strategies to target characteristics, integrating solid-phase, liquid-phase, and cell-based assays for high specificity and affinity. Multi-round enrichment and bioinformatics-guided analysis precisely capture high-value peptides, accelerating hit identification.
Rapid Validation & Optimization
Leveraging high-throughput sequencing and bioinformatics, we rapidly validate sequences and refine screening outcomes, reducing R&D timelines and costs.
One-Stop Solution
From library design to post-screening validation, we provide end-to-end support for drug development and mechanistic studies, ensuring a seamless transition from discovery to application.
Phage Display Peptide Library Screening Process
Fig.1 Phage Display Peptide Library Screening Platform
Phage Display Peptide Library Screening Workflow
| Process | Service Content | Timeline |
|---|---|---|
| 1. Target Immobilization and Peptide Library Incubation | Target molecules ( such as proteins, antibodies or cells ) are immobilized on solid-phase carriers and incubated with phages in the peptide display library to bind specific peptides to the target. | 1 day |
| 2. Elution and Enrichment | The non-specific binding phages were removed by low pH elution and competitive molecular elution, and the phages with high affinity were enriched. | 1 day |
| 3. Screening Cycle | After 3-4 rounds of screening, the strictness of screening conditions was gradually improved, and the specificity of the selected peptides to the target was enhanced. | 2-3 weeks |
| 4. Peptide Sequence Analysis | The enriched phages were analyzed by high-throughput sequencing to mine the optimal peptide sequence. | 1 week |
If you have any questions, please feel free to contact us at any time.
