Amakuru y'Ikigo
Icyiciro Cyerekana Ikoranabuhanga: Ibyiringiro byisoko niterambere ryubushakashatsi
Icyiciro Cyerekana Ikoranabuhanga: Isesengura ryisoko ryisoko niterambere ryubushakashatsi
Isesengura ry'Ubuvanganzo | Kabiri CD47 na PD-L1 Guhagarika Byongera CD8 + T Akagari Kurwanya Ibibyimba
Ubuvanganzo Umutwe: CD47 ebyiri na PD-L1 kuzibira bitera ubudahangarwa bwo kurwanya ibibyimba na selile intratumoral CD8 + T.
Isesengura ry'Ubuvanganzo | Igitabo VH3 Isomero rya Scaffold Yongera Imirongo imwe ya Antibody Ihamye
Ku ya 31 Nyakanga 2024, mu kinyamakuru Scientific Reports, Nam Ju Lee n'abandi. yasohoye urupapuro rwiswe Isomero rimwe rya antibody isomero rishingiye ku gutekinika-muntu-VH3 scafold.
Amakuru Yanyuma | Ibishya Nanobody Inhibitor yibasira virusi ya Ebola: Nanosota-EB1 & EB2
Ku ya 23 Ukuboza 2024, Umufana Bu n'abandi. yasohoye urupapuro rwiswe "Ivumburwa rya Nanosota-EB1 na -EB2 nka Novel Nanobody Inhibitor Kurwanya Indwara ya Ebola" mu kinyamakuru PLOS Pathogens.
Amakuru agezweho: IL-4 Itwara umunaniro wa CD8 + CART selile
Ku ya 12 Nzeri 2024, Carli M. Stewart na bagenzi be basohoye inkuru y'ingenzi mu itumanaho ry’ibidukikije, bagaragaza uruhare rwa Interleukin-4 (IL-mu gutwara umunaniro w’utugingo ngengabuzima twa CD8 + CAR T, ikintu gikomeye cy’ubuvuzi bwa selile CAR T. Iri terambere rishobora kugira ingaruka zikomeye ku masosiyete nka Alpha Lifetech Incorporation, agira uruhare runini mu guteza imbere tekinike y’ubudahangarwa.
Amakuru | Kwuzuza-Kugena Uturere Ihuriro rishobora gutera CAR-T Akagari kadakora neza
Ubushakashatsi buherutse gusohoka mu itumanaho ry’ibidukikije ku ya 13 Kanama 2023, bugaragaza ko ubwuzuzanye bugena akarere (CDR) mu gice kimwe gihinduranya urunigi (scFv) gishobora gutera CAR guteranya, biganisha ku bibazo bikomeye mu buvuzi bwa chimeric antigen reseptor (CAR) -T. Ingaruka z’ubu bushakashatsi zigaragaza imbogamizi zikomeye mu kuzamura imikorere y’ubuvuzi bwa CAR-T, hibandwa ku iperereza rigikomeje muri urwo rwego, cyane cyane ku masosiyete nka Alpha Lifetech Incorporation, yihaye guteza imbere ikoranabuhanga rya CAR.
Amakuru agezweho | Ubushakashatsi bushya bwerekana ubushobozi bwo guhindura kanseri
Ku ya 1 Kamena 2024, mu kinyamakuru Nature Communications, abahanga bo mu itsinda ry’ubushakashatsi bwa Bo Li basohoye inkuru yiswe "Area postrema neurons mediate interleukin-6 imikorere ya kanseri cachexia". Iyo ngingo yasanze kuzamuka kwa interleukin-6 bishobora gutera ubwonko gukora nabi ndetse amaherezo na kanseri ya kanseri.
Amakuru agezweho | Icyiciro cya mbere-Cyiciro Cyatoranijwe Cyibuza cya EGFR na PI3K gitanga uburyo bumwe-bwa molekile uburyo bwo kwibasira kurwanya imihindagurikire y'ikirere.
Ku ya 11 Nyakanga 2024, itsinda ry’abashakashatsi riyobowe na Dr. Judith Sebolt Leopold ryateguye inzitizi ya kinase inhibitor MTX-531 ishobora guhagarika ibyorezo byiyongera (EGFR) na phosphatidylinositol 3-OH kinase (PI3K).