Serivisi yo kuvumbura abasirikari ba Fab

Alpha Lifetech Inc.irashobora gutanga ubwoko butandukanye cyangwa ubwoko butandukanye bw'ama-isotype y'ama-antibody ya Fab asanzwe cyangwa yakozwe hashingiwe ku buryo bwacu bwo kwerekana ikoranabuhanga rya phage ikuze. Kubaka ama-antibody meza afite ingano nini y'ama-antibody n'ubwoko bwinshi byagize akamaro kanini mu gutuma ama-antibody amenyekana neza, bizatuma habaho kwihuta mu kuvumbura ama-antibody n'imiti.Alpha Lifetech'sItsinda ry’ubushakashatsi n’iterambere ry’abashakashatsi ku byavumbuwe na antibody ritewe ishema no gutangaza ko dushobora gukora isomero rya Fab ryakozwe rifite imiterere yigenga irenga 10^11.

Antibody ya Fab ni iki?

Molekile ya IgG ishobora kugabanywamo ibice bibiri by'ingenzi: (1) igice gishobora gucukurwa (Fc), kigize umurizo w'umubiri kandi kigakorana n'udukingirizo tw'uturemangingo kugira ngo gikoreshwe mu buryo bw'ubudahangarwa bw'umubiri, na (2) icyuma gifata antigen (Fab), gihuza kumenya antigen. Agace ka Fc kagizwe n'ibice bibiri by'udukingirizo tudahinduka (CH2 na CH3) bivuye mu minyururu ibiri iremereye, mu gihe agace ka Fab k'umubiri kagizwe n'udukingirizo tudahinduka gakurikirwa n'udukingirizo tudahinduka duturutse mu munyururu uremereye (VH na CH, uko bikurikirana), duhuzwa n'udukingirizo tudahinduka n'udukingirizo tudahinduka duturutse mu munyururu uremereye (VL na CL, uko bikurikirana).

Ikoranabuhanga ryo kwerekana ubudahangarwa bwa Fab-Phage

Amasomero ya Fab, aho imiterere y’uturemangingo tw’urumuri (LC) n’uturemangingo tw’uruhererekane rurerure (HC) ishyirwa mu itsinda ry’udusimba tw’uruhererekane rw’udusimba hanyuma ikagaragara ku buso bw’agace k’udusimba tw’uruhererekane rw’udusimba, yakoreshejwe cyane mu gutandukanya uturemangingo tw’umubiri (Abs) hamwe n’imiterere yihariye ya haptens, antigens zo mu mahanga (Ags), na self Ags.
Alpha Lifetech ishobora gutanga serivisi yo kubaka no gusuzuma isomero rya Fab gakondo ndetse na serivisi yo kubaka no gusuzuma isomero rya Fab rya sintetike.

Hagati aho, Alpha Lifetech itanga amasomero ya Fab Antibody yiteguye gukoreshwa, agaragara neza mu buryo bwa phage kugira ngo yihutishe inzira yawe yo kuvumbura antibody. Yagenewe guhaza ibyifuzo bikomeye by'ubushakashatsi, amasomero yacu atanga Iterambere Ridasanzwe, Ubudasa Bunini, n'Ubushobozi Bunini hamwe n'Ubusumbane Buto bwo Guhitamo. Ubu dutanga amasomero ya Fab y'abantu ahamye kandi atandukanye, agenewe gutanga urufatiro rukomeye rw'iterambere ry'ubuvuzi n'isuzumabumenyi.

Kuki twahitamo?

● Guhindura Vektori
Abahanga bacu banahinduye sisitemu ya vector ifite ibintu byinshi, nko gutandukanya umurongo w’ubuyobozi ku miyoboro yoroheje n’iremereye, kodoni yo guhagarika ituma byoroha kohereza hagati y’ubwoko bukwiye bw’ibinyabutabire mu gutegura phage cyangwa kugaragaza Fab isoluble, ikimenyetso cya Myc cyo gusesengura no gutunganya poroteyine, hamwe n’ahantu hatandukanye hashyirwa poroteyine mu buryo bw’ingirakamaro mu kugarura phage iboshye mu gihe cyo gusuzuma isomero.

● Ingamba zo Guhindura Ishusho
Kugira ngo hubakwe isomero rinini ry’abasilikare barinda indwara, Alpha Lifetech Inc. ikoresha ingamba nziza zo gushushanya mu kubaka isomero rya antibody phage hashingiwe ku gutandukanya ibice by’ibice bibuza indwara biva muri vectors za plasmid aho gukoresha PCR.

● Serivisi ihoraho
Dufite ubumenyi bwimbitse ku ikoranabuhanga rya porogaramu yo kwerekana antibody phage, dushobora guhindura umushinga wawe kugira ngo uhuze n’inyubako imwe n’imwe no gusuzuma antibody, tugafasha abakiriya mu bibazo byose bigiye kubaho ndetse no mu kubaka no gusuzuma isomero.

Serivisi zijyanye na Fab AntibodySERIVISI ZIFITE IF ...