Serivisi yo kuvumbura Fab
Itsinda ryavumbuye antibody ya Alpha Lifetech ryishimiye gutangaza ko dushobora guteza imbere isomero rya Fab hamwe na clone yigenga irenga 10 ^ 11.
TWANDIKIRESerivisi yo kuvumbura Fab
Yamazaki Inc.ishoboye gutanga amoko atandukanye cyangwa isotypes zitandukanye zamasomero kavukire cyangwa synthes ya Fab antibody yububiko bushingiye kumurongo witerambere rya tekinoroji ya fage. Kubaka isomero ryiza rya antibody rifite ubunini bunini bwibitabo nubunini butandukanye byabaye ingenzi cyane mugutandukanya neza antibodi, bizavamo umuvuduko wo kuvumbura antibody-ibiyobyabwenge. NonehoAlpha Lifetech'santibody kuvumbura itsinda R&D ryishimiye gutangaza ko dushobora guteza imbere isomero rya Fab hamwe na clone yigenga irenga 10 ^ 11.
Antibody Fab ni iki?
Molekile ya IgG irashobora kugabanywamo ibice bibiri bikora: (1) agace kristallizable (Fc), kagizwe umurizo wa antibody kandi igahuza niyakirwa ryimyanya ndangagitsina kugirango itangire ubudahangarwa bw'umubiri, kandi (2) guhuza ibice-antigen (Fab), ihuza kumenyekanisha antigen. Agace ka Fc kagizwe na joriji ebyiri za domaine zihoraho (CH2 na CH3) ziva muminyururu ibiri iremereye, mugihe akarere ka Fab ka antibody kagizwe numuyoboro uhindagurika ukurikirwa numuyoboro uhoraho uva kumurongo uremereye (VH na CH, uko bikurikirana), ugahuza hamwe numuyoboro uhinduka kandi uhoraho kuva kumurongo wumucyo (VL na CL).
Fab Antibody Iterambere-Icyiciro Cyerekana Ikoranabuhanga
Amasomero ya Fab, aho urunigi rwumucyo (LC) hamwe nuruhererekane rwinshi (HC) rwahinduwe mukarere ka fagemide hanyuma bikerekanwa hejuru yubutaka bwa fagile, byakoreshejwe cyane mugutandukanya antibodiyite (Abs) zifite umwihariko wa haptens, antigene zamahanga (Ags), hamwe na Ags.
Alpha Lifetech irashobora gutanga ububiko bwibitabo bwa Fab bwububiko bwa serivisi hamwe nogusuzuma hamwe na serivise yububiko bwa Fab.
Kuki Duhitamo?
● Guhindura ibice
Abahanga bacu kandi bahinduye sisitemu ya vector ifite ibintu byinshi, nkubuyobozi butandukanye bwurutonde rwumucyo nu munyururu uremereye, codon yo guhagarika yemerera guhinduranya byoroshye hagati yabakiriye neza kugirango bategure fage cyangwa imvugo ya elegitoronike Fab, tag ya Myc yo gusesengura no kweza poroteyine, hamwe na subtilisin cleavage site ifite akamaro ko kugarura fage mugihe cyo gusuzuma isomero.
● Ingamba zo Gukwirakwiza
Mu rwego rwo kubaka isomero rinini rya antibody, Alpha Lifetech Inc. ikoresha ingamba nziza zo gukwirakwiza cloni yo kubaka amasomero ya antibody ya fage ishingiye ku gutandukanya ibice byabuzanyijwe biva mu bice bya plasmid aho kuba ibicuruzwa bya PCR.
● Serivisi imwe
Hamwe no gusobanukirwa byimbitse ya tekinoroji ya antibody fage yerekana isomero, turashobora guhuza umushinga wawe mukubaka rimwe hamwe no kwerekana amasomero ya antibody, gufasha abakiriya nibibazo byose biri imbere nibibazo byubaka isomero no kwerekana.
Fab Antibody Serivisi ijyanyeUMURIMO UFitanye isano
Serivisi ishinzwe kubaka Isomero rya Antibody
Alpha Lifetech ifite gahunda yo kubaka isomero rya Fab antibody ikuze, ishobora kubaka amasomero ya Fab antibody ku bantu n’inyamaswa zitandukanye, harimo amasomero y’ubudahangarwa, amasomero kavukire, amasomero ya sintetike, amasomero yubukorikori nibindi, bishobora guhuza ibyifuzo bitandukanye byabakiriya.
Shakisha
Serivisi yo Kugenzura Isomero rya Fab
Alpha Lifetech irashobora kwerekana amasomero atandukanye ya fage ashingiye kuri M13, T4, T7 na λ uhereye kubantu, imbeba, urukwavu, inkoko, intama n'ingamiya ukurikije ibyo abakiriya bacu bakeneye.
Shakisha
Serivisi yo Kwerekana Antibody
Alpha Lifetech irashobora gukora antibodiyite za Fab muburyo bwinshi mugutezimbere umuco, imiterere yerekana imiterere, uburyo bwo kwandura, nibindi kugirango bikoreshwe mubuvumbuzi bwibiyobyabwenge, ibinyabuzima nizindi nzego
Shakisha
Serivisi yo Kweza Antibody
Alpha Lifetech yoza antibodiyite za Fab ziva mumico ndengakamere na serumu na chromatografi ya affinity, kandi ubuziranenge bwa antibodi zeze bushobora kugera kuri 95%.
Shakisha
Serivisi ya Antibody Biotinylation
Serivise ya antibody antibody ya biotinylation itangwa na Alpha Lifetech nubuhanga bukora cyane bwa antibody yerekana ibimenyetso byongera imbaraga zo gutahura no gutuza kwa antibodi muguhuza hamwe na molekile ya biotine na antibodi ya Fab.
Shakisha
Serivisi ishinzwe ubushakashatsi bwa Fab Antibody
Suzuma byimazeyo imikorere niterambere rya antibodies za Fab, utange amakuru yimbitse aranga.WB, IHC, ICC, NIBA, ELISA, IP, ChIP, peptide array, isesengura rya cytometrike (FC)
Shakisha
Serivisi ishinzwe ubumuntu
Ukurikije antibody yumwimerere yatanzwe nu mukiriya, kugereranya no kugereranya kubara bikorwa kugirango hategurwe ingamba zabantu.
Shakisha
Fab Antibody Service Service
Alpha Lifetech igera kuri antibodi zihamye kuri biotine, HRP, na isotopes binyuze muburyo bworoshye bwo kuranga, ibyo bikaba bitezimbere cyane ibyiyumvo byihariye kandi byihariye.
Shakisha
Serivisi yo kubaka isomero rya Naïve Fab
Ubwoko bwinshi bwamasomero ya Fab antibody: amasomero yumubiri, amasomero kavukire, amasomero yubukorikori, nibindi dukwirakwiza serivise zo hejuru no kumanuka ziva mubikorwa bya fab antibody
Shakisha
Serivisi yo Kugenzura Isomero rya Naïve Fab
Binyuze mu byerekezo 2-3 byo guhanagura, antibodies za Fab zihuza na antigene zitandukanye zifitanye isano cyane zirashobora kwigunga mugihe cyiminsi 12 bitabaye ngombwa gukingira inyamaswa, bigabanya igihe cyo gukora antibody ya Fab. Amasomero ya naïve arimo umubare munini wa antibody ikurikirana.
Shakisha
Serivisi yo kubaka Isomero rya Fab
Ubwoko bwinshi bwibitabo bya Fab antibody: amasomero yumubiri, amasomero kavukire, amasomero yubukorikori, nibindi.Alpha Lifetech ifite urubuga rwuzuye rwa M13 / T7 rwo kwerekana ibyubaka no gutanga amasomero ya antibody.
Shakisha
Serivisi yo Kugenzura Isomero rya Fab
Binyuze mu byerekezo 2-3 byo gutekesha, antibodies za Fab zihuza na antigene zitandukanye zifitanye isano cyane. Alpha Lifetech irashobora kandi guha abakiriya icyerekezo cyo guhitamo icyiciro cya nanobody cyerekana, icyerekezo cya scFv, hamwe na Fab yerekana.
Shakisha
Serivisi ya Fab
Alpha Lifetech irashobora kandi gutanga serivisi zabigenewe nko gukora antibody ya Fab, label ya antibody, guhuza antibody, hamwe no kwinjiza antibody nyinshi kugirango uhuze ibyo ukeneye.
ShakishaNiba ufite ikibazo, nyamuneka twandikire igihe icyo aricyo cyose.
2018-07-16 
