Urubuga rwa Poroteyine y'Umubiri

Alpha Lifetech yashyizeho serivisi yuzuye ihuriweho yo gukora poroteyine, gutunganya poroteyine, no kugenzura imikorere yayo. Dufite ubunararibonye bwinshi mu gukora poroteyine zivanze mu buryo bwihariye no gukora poroteyine zivanze. Twateguye neza ibihumbi bya poroteyine zivanze ku bakiriya bacu, harimo antibodies zivanze mu mubiri, poroteyine zisohoka, poroteyine zinyura mu ruhu, poroteyine, nibindi, kandi bitera imbere cyane.

Ikoreshwa n'ishyirwa mu byiciro rya poroteyine zo mu ruhu

Dukurikije aho ziherereye, poroteyine zigabanyijemo poroteyine zo mu ngirabuzimafatizo, poroteyine zo mu ngirabuzimafatizo, na poroteyine zo hanze y’umubiri. Muri zo, poroteyine zo mu ngirabuzimafatizo zigize hafi 30% by’uturemangingo twose tw’umubiri kandi zigira uruhare runini mu bikorwa by’ubuzima bw’uturemangingo. Iyo poroteyine zo mu ngirabuzimafatizo zikoze nabi, bishobora gutera indwara zitandukanye. Urugero, iyo urugero rw’imyitwarire ya receptor y’ubukure bwa pituitary na receptor y’ubukure bwa 2 (HER2) ku buso bw’uturemangingo ruri hejuru, bishobora gutera kwiyongera no gutandukana kudasanzwe kw’uturemangingo, ndetse bigatera kanseri. Guhuza hagati y’uturemangingo tw’imiti na poroteyine zo mu ngirabuzimafatizo akenshi bifitanye isano n’imikorere y’imiti. Kubwibyo, kwiga imiterere n’imikorere ya poroteyine zo mu ngirabuzimafatizo bishobora gutanga ibitekerezo bimwe na bimwe byo guteza imbere imiti. Mu gusobanukirwa imikoranire hagati y’imiti na poroteyine zo mu ngirabuzimafatizo, imikorere y’imiti ishobora kunozwa kandi ingaruka mbi zishobora kugabanuka. Poroteyine zo mu ngirabuzimafatizo zishobora kandi gukoreshwa nk’intego y’imiti, bityo zishobora gukoreshwa mu kuvura indwara zitandukanye nka kanseri n’indwara z’umutima binyuze mu kubangamira imikorere ya poroteyine zo mu ngirabuzimafatizo. Poroteyine zo mu ngirabuzimafatizo zishobora kumenya by’umwihariko ibintu byibandwaho. Hashingiwe kuri ubu bushobozi bwihariye bwo kumenya, poroteyine zo mu ruhu zishobora kuba igice cy'ingenzi cy'ibikoresho by'ibinyabuzima, bigatuma zishobora kumenya neza ibintu bitandukanye biri imbere no hanze y'umubiri, birimo imiti, imisemburo, bagiteri na virusi.

Poroteyine zo mu ruhu zigabanyijemo ibice bitatu, birimo poroteyine zo mu ruhu, poroteyine zo mu ruhu, na poroteyine zifata lipide.

Igishushanyo cya 1 Imiterere ya poroteyine zo mu rukenyerero n'uburyo ibinure bigenzurwa.(Ifoto y'aho yaturutse: Gukurikirana Imiterere ya Poroteyine y'Umubiri mu Gihe Nyacyo - PMC (nih.gov))

poroteyine zo mu ruhu rw'imbere

Poroteyine zo mu ruhu rw'inyuma zivuga poroteyine zishongesha mu mazi zifatana na molekile za poroteyine cyangwa molekile za lipide zo mu ruhu rw'inyuma zikoresheje imigozi ya ioni cyangwa izindi migozi zidahuje neza. Izi poroteyine zikwirakwira cyane cyane ku ruhu rw'imbere rw'uruhu kandi zifite imbaraga nke zo gufatana n'uruhu. Kubwibyo, igihe cyose imbaraga za ioni z'umuti zihindutse cyangwa ubushyuhe bwiyongere, poroteyine zo mu ruhu rw'inyuma zizatandukana n'uruhu, bigatuma gutunganya poroteyine byoroha.

Poroteyine zivanze

Poroteyine z’urusobe rw’amatafari zigize poroteyine zivuga poroteyine zikorana n’urusobe rw’amatafari binyuze mu mikoranire ikomeye y’amazi, bityo zigashyira cyangwa zigashyira mu rusobe rw’amatafari yose. Bitewe n’ubushobozi bwazo bwo gukora helice za transmembrane mu rusobe rw’amatafari, izi poroteyine zifatanya cyane n’urusobe rw’amatafari kandi ntizoroshye gushonga mu mazi. Poroteyine z’urusobe rw’amatafari zigize membrane, zizwi kandi nka poroteyine za transmembrane, zishobora kugabanywamo domaine yo hanze y’amatafari, domaine ya transmembrane, na domaine yo hagati y’amatafari. domaine ya transmembrane ubusanzwe igizwe na alpha helices, ari zo bice bya hydrophobic bikorana n’imirizo ya molecules za membrane kandi bigashyirwa mu rusobe rw’amatafari. Guhuza poroteyine za membrane bigira ingaruka zikomeye ku buryo imiterere ya membrane ihamye.

Poroteyine zifatanye n'ibinure

Poroteyine zifatanye n'ibinure zitwa lipide bivuze poroteyine zigira uruhare mu gufatana n'ibinure binyuze mu migozi ihuza ibice bibiri (covalent bonds) zigafatana n'ibinure bya cytoplasme. Poroteyine zifatanye n'ibinure zishobora kuba ku mpande z'imbere n'inyuma z'ibinure, kandi gufatana kwazo n'ibinure bikaba bihamye.

Serivisi zijyanye

Alpha Lifetech yashyizeho serivisi yuzuye ihuriweho yo kugaragaza poroteyine, kuyisukura no kuyigenzura.

Serivisi yo kugaragaza poroteyine mu rukenyerero

Serivisi yo gutanga poroteyine ya Alpha Lifetech itanga ibisubizo bigezweho mu gukora poroteyine zigoye za membrane, harimo GPCRs, inzira za ion, n'uduce tumeze nka virusi.

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Serivisi yo gusukura poroteyine mu rukenyerero

Alpha Lifetech izahitamo uburyo bwo gusukura hakurikijwe ibyo abakiriya bacu bakeneye, kandi ibuhuze n'urubuga rwacu rwo gusukura poroteyine kugira ngo babone ibikoresho byiza bya poroteyine mu gihe gito.

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