Serivisi yo kweza poroteyine

Alpha Lifetech yateguye neza poroteyine ibihumbi n'ibihumbi za recombinant kubakiriya bacu, harimo antibodiyite za recombinant, proteine zasohotse, poroteyine za transembrane, protease, nibindi, hamwe niterambere ryinshi. Abakiriya bakeneye gusa gutanga urutonde rwa poroteyine, CDS cyangwa izina rya poroteyine, kandi Alpha Lifetech irashobora guteza imbere poroteyine yuzuye ya fusion protein hamwe na gahunda yo kweza mugihe gito. Turashobora gutanga poroteyine yihariye ya serivise ishingiye kuri sisitemu enye zingenzi zerekana imvugo, hanyuma tugahitamo imvugo itandukanye ya fusion protein hamwe nuburyo bwo kweza dukurikije ibyo abakiriya bakeneye.

Alpha Lifetech ifite ibikoresho bitandukanye byo kweza poroteyine n'ibikoresho, bishobora gutanga isuku ya poroteyine karemano hamwe na serivisi zo kweza poroteyine za recombinant, nko kweza inkomoko, chromatografiya ya molekile, chromatografi ya ion, na chromatografiya ya hydrophobique. Tuzahitamo uburyo bwo kweza dukurikije ibyo abakiriya bacu bakeneye, kandi tubihuze hamwe na porogaramu yo kweza poroteyine kugirango tubone ibicuruzwa byiza bya poroteyine nziza mu gihe gito.

Itondekanya poroteyine za Membrane

Ukurikije ikwirakwizwa rya poroteyine muri membrane hamwe n’umubano uri hagati ya poroteyine ya membrane na lipide ya membrane, poroteyine zo mu bwoko bwa membrane zigabanyijemo ibyiciro bitatu, harimo poroteyine zo mu bwoko bwa peripheri, poroteyine zihuriweho, hamwe na poroteyine za lipide.

Umuyoboro wa poroteyine

Ionic umuyoboro wa poroteyine ni poroteyine ihuriweho na poroteyine yinjira mu binyabuzima kugira ngo ikore imiterere yihariye y’umuyoboro, ihitamo kwemerera ion zimwe na zimwe gutwarwa muri membrane imbere no hanze y’akagari, mu gihe ibuza izindi ion kunyuramo. Guhitamo poroteyine zo mu muyoboro wa ion ni ingenzi cyane mu gukomeza imirimo y’ubuzima bwa selile nko gutandukanya ubukana bwa ion hagati y’akagari, ubwikorezi bwa neurotransmitter, nibindi.

G proteine ihujwe na reseptor

G proteine ihujwe niyakirwa ni ijambo rusange kumurongo munini wa reseptor ya membrane proteine, nizo nyinshi zakira selile zo hejuru muri eukaryote. Igikorwa nyamukuru cya G proteine zifatanije ni ugukwirakwiza amakuru adasanzwe mumbere ya selile binyuze mumikoranire ya G proteine, bigira uruhare runini mugukwirakwiza ibimenyetso. G poroteyine ihujwe na reseptor imenya kandi igahuza ligand idasanzwe kugirango itume inzira yerekana ibimenyetso, bityo igenga ibikorwa bitandukanye byimikorere ya selile.

Virus Nka Ibice

Virusi nkigice ni poroteyine igizwe no kwishyira hamwe kwa poroteyine imwe cyangwa nyinshi zubaka za virusi. Ibi bice bisa na morphologie n'imiterere ya virusi ya virusi, ariko ntabwo irimo ibintu bikomoka kuri virusi, kubwibyo ntabwo byanduye.

Virus Nka Particles irashobora kuba urubuga rwo kwerekana poroteyine za membrane, bigereranya ihinduka n'imikorere ya poroteyine za membrane mu bidukikije karemano zerekana poroteyine zihariye kuri virusi nka Particles. Mu iterambere ry’inkingo, antigene ikingira virusi, ubusanzwe poroteyine ya membrane, irashobora kwerekanwa kuri Virus Nka Particles kugirango itume umubiri utanga ubudahangarwa bw'umubiri urwanya izo antigene. Inkingo zateguwe binyuze muri ubu buryo zifite umutekano muke kandi zikingira indwara.

Isuku rya poroteyine za Membrane

Hariho uburyo butandukanye bwo kweza poroteyine za membrane, muri zo harimo chromatografi ya affinity ikoresha isano ya poroteyine za membrane ubwazo cyangwa ibimenyetso bya fusion, nka tagi ye, hamwe na ligande zihariye kugirango bigere kuri proteine yo kweza no gutandukana. Ion guhana chromatografiya ikoresha ibintu byishyurwa bya proteine za membrane kugirango ubitandukanye kuri ion yo guhanahana. Nyamara, ibisubizo bya poroteyine ya membrane bikunze kubamo ibintu, kandi kwegura bishobora kugira ingaruka kumikorere ya chromatografiya. Gel filtration ya chromatografiya ni ugukoresha itandukaniro ryuburemere bwa poroteyine ya poroteyine kugirango itandukane ku nkingi ya gel, binyuze muri ubu buryo, dushobora kubona proteine nziza cyane. Bitewe nubusabane hamwe na hydrophobique ya proteine za membrane, zirashobora gutandukana kumurongo wa chromatografique. Ubu buryo bukora neza, bwihuse, kandi bworoshye cyane, ariko ikiguzi nacyo kiri hejuru.

membrane protein yoza-Alpha Lifetech