Serivisi yo gusukura poroteyine mu rukenyerero

Alpha Lifetech yateguye neza ibihumbi bya poroteyine zivanze ku bakiriya bacu, harimo antibodies zivanze, poroteyine zisohoka, poroteyine za transmembrane, poroteyine, nibindi, hamwe n'ibipimo byo gutsinda biri hejuru. Abakiriya bakeneye gusa gutanga urukurikirane rwa poroteyine, CDS cyangwa izina rya poroteyine, kandi Alpha Lifetech ishobora gutegura gahunda yuzuye yo guhuza poroteyine no kuyisukura mu gihe gito. Dushobora gutanga serivisi zihariye zo guhuza poroteyine hashingiwe ku buryo bune bw'ingenzi bwo guhuza, no guhitamo ingamba zitandukanye zo guhuza poroteyine no kuyisukura hakurikijwe ibyo abakiriya bakeneye.

Alpha Lifetech ifite ibikoresho bitandukanye byo gutunganya poroteyine, bishobora gutanga serivisi zo gutunganya poroteyine karemano no gutunganya poroteyine zivanze, nko gutunganya affinity, chromatography ya molecular sieve, chromatography ya ion exchange, na chromatography ya hydrophobic. Tuzahitamo uburyo bwo gutunganya hakurikijwe ibyo abakiriya bacu bakeneye, kandi tubihuze na platform yacu yo gutunganya poroteyine kugira ngo tubone ibicuruzwa bya poroteyine byiza mu gihe gito.

Ishyirwa mu byiciro rya poroteyine zo mu rukenyerero

Dukurikije uko poroteyine zikwirakwira mu rurerure ndetse n'isano iri hagati ya poroteyine zo mu rurerure n'ibinure byo mu rurerure, poroteyine zo mu rurerure zigabanyijemo ibice bitatu, birimo poroteyine zo mu rurerure rw'inyuma, poroteyine zo mu rurerure rw'inyuma, na poroteyine zifata ibinure.

Poroteyine y'umuyoboro wa Ionic

Poroteyine y'umuyoboro wa Ionic ni poroteyine y'umuyoboro ihuriweho yinjizwa mu ngirabuzimafatizo z'ibinyabuzima kugira ngo ikore imiterere yihariye y'umuyoboro, ikemerera iyoni zimwe na zimwe kujyanwa mu ngirabuzimafatizo imbere no hanze y'ingirabuzimafatizo, mu gihe ikabuza izindi iyoni kunyuramo. Guhitamo poroteyine z'umuyoboro wa Ionic ni ingenzi mu kubungabunga imikorere y'ubuzima bw'ingirabuzimafatizo nko gutandukanya ingano ya iyoni hagati y'imbere n'inyuma y'ingirabuzimafatizo, gutwara neurotransmitter, n'ibindi.

Receptors zihujwe na poroteyine ya G

Recepteur za G zihujwe na poroteyine ni ijambo rusange rikoreshwa mu itsinda rinini rya recepteur za poroteyine zo mu ruhu, zikaba ari zo recepteur nyinshi cyane zo hejuru y’uturemangingo muri eukaryotes. Akamaro nyamukuru ka recepteur za G zihujwe na poroteyine ni ugutanga amakuru yo hanze y’uturemangingo imbere mu turemangingo binyuze mu gukorana na poroteyine ya G, bigira uruhare runini mu gutuma ibimenyetso bitangwa. Recepteur za G zihujwe na poroteyine zigira kandi zigafatana na ligande zo hanze y’uturemangingo kugira ngo zitere inzira zo mu turemangingo, bityo zigatunganya ibikorwa bitandukanye by’umubiri by’uturemangingo.

Uduce dusa na virusi

Agace kameze nk'agakoko ka virusi ni agace ka poroteyine gakozwe no kwihuza kwa poroteyine imwe cyangwa nyinshi z’imiterere ya virusi. Utu duce dusa mu miterere n’imiterere y’utundi duce karemano twa virusi, ariko ntabwo tuba dufite imiterere ya genetiki ya virusi, bityo ntabwo yandura.

Ibice Bimeze nk'ibya Virusi bishobora gukoreshwa nk'urubuga rwo kwerekana poroteyine z'urukiramende, biganisha ku miterere n'imikorere ya poroteyine z'urukiramende mu bidukikije karemano binyuze mu kwerekana poroteyine zihariye z'urukiramende kuri Virusi Bimeze nk'ibya Virusi. Mu ikorwa ry'inkingo, antigens zirinda virusi, akenshi poroteyine z'urukiramende, zishobora kwerekanwa kuri Virusi Bimeze nk'ibya Virusi kugira ngo zikangure umubiri gukora ubudahangarwa bw'umubiri kuri izi antigens. Inkingo zitegurwa muri ubu buryo ni nziza cyane kandi zirinda indwara.

Gusukura poroteyine zo mu rukenyerero

Hari uburyo butandukanye bwo gusukura poroteyine zo mu ruhu, muri bwo chromatography y’ubumwe ikoresha ubwinshi bwa poroteyine zo mu ruhu ubwazo cyangwa tagi zo guhuza, nka tagi za His, hamwe na ligands zazo zihariye kugira ngo hagerwe ku gutunganya no gutandukanya poroteyine zo mu ruhu. Chromatography yo guhinduranya iy’ubwonko ikoresha imiterere ya poroteyine zo mu ruhu kugira ngo izitandukanye ku ma resini yo guhinduranya iy’ubwonko. Ariko, ibisubizo bya poroteyine zo mu ruhu akenshi biba birimo isabune, kandi kureka gusohora bishobora kugira ingaruka ku mikorere ya chromatography yo guhinduranya iy’ubwonko. Chromatography yo gutunganya iy’ubwonko ikoresha itandukaniro ry’uburemere bwa poroteyine zo mu ruhu kugira ngo zitandukane ku nkingi ya gel, binyuze muri ubu buryo, dushobora kubona poroteyine zo mu ruhu zisukuye cyane. Bitewe n’ubwinshi n’ubudahangarwa bwa poroteyine zo mu ruhu, zishobora gutandukanywa ku nkingi za chromatography. Ubu buryo burakora neza, bwihuse, kandi bugira ingaruka cyane, ariko igiciro nacyo ni kinini.

gutunganya poroteyine mu rukenyerero - Alpha Lifetech